2454-36-6Relevant academic research and scientific papers
2,4-bis-substituted acetophenone compound, optical isomers and pharmaceutically acceptable salts thereof and application of 2,4-bis-substituted acetophenone compound and optical isomers and pharmaceutically acceptable salts thereof
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, (2017/12/28)
The invention relates to a 2,4-bis-substituted acetophenone compound and optical isomers and pharmaceutically acceptable salts thereof. The invention further discloses an application of the 2,4-bis-substituted acetophenone compound and the optical isomers and pharmaceutically acceptable salts thereof in the aspect of treatment of neural degeneration diseases. The novel compounds have acetylcholinesterase inhibition activity and A beta aggregation inhibiting ability, and hydrolyzates of the novel compounds further have a metal ion chelation action, so that the novel compounds can be used for carrying out treatment from a plurality of targets and have a better application prospect in the treatment of the neural degeneration diseases.
