24544-05-6Relevant academic research and scientific papers
Palladium-catalyzed amidation by chemoselective C(sp3)-H activation: Concise route to oxindoles using a carbamoyl chloride precursor
Tsukano, Chihiro,Okuno, Masataka,Takemoto, Yoshiji
supporting information; experimental part, p. 2763 - 2766 (2012/05/05)
Quite select: A new strategy was developed for the synthesis of various oxindoles from carbamoyl chlorides. Under the optimum reaction conditions, with Ad2PBu as a ligand, tBuCONHOH as an additive, and a CO atmosphere, selective C(sp3/sup
Revisitation of Formaldehyde Aniline Condensation. VIII. - Monomeric N-Methylene Anilines
Giumanini, Angelo G.,Verardo, Giancarlo,Polana, Marco
, p. 161 - 174 (2007/10/02)
A convenient, high yield "dry" method of synthesis of monomeric N-methyleneanilines (6a-i) and the characterization of the products by m.s., 1H- and 13C-n.m.r. and i.r. are reported, improving previous procedures and describing new compounds.It appeared that the existence of monomeric N-methyleneanilines is stricly related to the presence of enough steric hindrance to oligomerization by substituents in ortho positions.Moreover, some addition products of formaldehyde to an amine and its corresponding imines are tentatively identified on the basis of the observed mass spectrum of the whole reaction mixture.The reaction products of formaldehyde with 2,6-dimethylaniline (1a) provided an example of a mobile equilibrium between monomeric and trimeric imine.
