245660-14-4

Basic information

• Product Name: {2S-[2α,3β(S)]}-3({[3-Phenyl-1-(carboxyl)propyl]amino}carbonyl)oxirane carboxylic acid ethyl ester
• Synonyms: {2S-[2α,3β(S)]}-3({[3-Phenyl-1-(carboxyl)propyl]amino}carbonyl)oxirane carboxylic acid ethyl ester
• CAS NO: 245660-14-4
• Molecular Weight: 321.33
• Mol File: 245660-14-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {2S-[2α,3β(S)]}-3({[3-Phenyl-1-(carboxyl)propyl]amino}carbonyl)oxirane carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {2S-[2α,3β(S)]}-3({[3-Phenyl-1-(carboxyl)propyl]amino}carbonyl)oxirane carboxylic acid ethyl ester(245660-14-4)
• EPA Substance Registry System: {2S-[2α,3β(S)]}-3({[3-Phenyl-1-(carboxyl)propyl]amino}carbonyl)oxirane carboxylic acid ethyl ester(245660-14-4)

Safety Data

• Hazardous Substances Data: 245660-14-4(Hazardous Substances Data)

Upstream product

• 117560-24-4 p-tolylsulfonic caid salt of L-homophenylalanine benzyl ester 
• 63734-73-6 ethyl (2S,3S)-2,3-epoxysuccinate 
• 245660-09-7 {2S-[2α,3β(S)]}-Oxirane carboxylic acid 3-[({3-Phenyl-1-[(benzyloxy)carbonyl]propyl}amino)carbonyl] ethyl ester 

Downstream Products

• 245660-32-6 {2S-[2α,3β(S)]}-3-{[(3-Phenyl-1-{[(5-hydroxypentyl)amino]carbonyl}propyl)amino]carbonyl}oxirane carboxylic acid ethyl ester 
• 245660-28-0 {2S-[2α,3β(S)]}-3-{[(3-Phenyl-1-{[(5-t-butyldimethylsilanoxylpentyl)amino]carbonyl}propyl)amino]carbonyl}oxirane carboxylic acid ethyl ester 

Relevant articles and documents

A new synthesis of peptidyl epoxysuccinates for probing cysteine protease-inhibitor P3/S3 binding interactions

A new synthesis of peptidyl epoxysuccinates has been developed involving the N-acylation of amino acid benzyl esters (12) with the tartrate ester derived epoxy acid 13 followed by deprotection of the benzyl esters and acylation with amines 21-28. This syn