245748-61-2

Downstream Products

• 251655-58-0 6-[(3-[1,3]Dioxolan-2-yl-propoxy)]-N-[4-(5-cyano-3-pyridin-3yl-pyrazol-1-yl)phenyl]nicotinamide 
• 251655-66-0 [4-(5-Cyano-3-pyridin-3-yl-pyrazol-1-yl)phenyl]-(2,6-dimethylbenzyl)-amine 
• 251655-65-9 (2-Chloro-6-fluorobenzyl)-[4-(5-cyano-3-pyridin-3-yl-pyrazol-1-yl)phenyl]amine 
• 251655-64-8 [4-(5-Cyano-3-pyridin-3-yl-pyrazol-1-yl)phenyl]-(2-indanylmethyl)amine 
• 251655-56-8 6-[(3-Cyanopropoxy)]-N-[4-(5-cyano-3-pyridin-3-yl-pyrazol-1-yl)phenyl]nicotinamide 
• 251655-70-6 [4-(5-Cyano-3-pyridin-3-yl-pyrazol-1-yl)phenyl]-[4-(3-cyanopropoxy)benzyl]-amine 
• 251655-67-1 [4-(5-Cyano-3-pyridin-3-yl-pyrazol-1-yl)phenyl]-(2-chloro-6-methylbenzyl)amine 

Relevant academic research and scientific papers

Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents

1-(4-aminophenyl)pyrazoles optionally substituted on the 3- and 5-positions of the pyrazole ring and on the amino group at the 4-position of the phenyl ring are disclosed and described, which pyrazoles inhibit IL-2 production in T-lymphocytes.

AZOLE INHIBITORS OF CYTOKINE PRODUCTION

Compounds having the formula are useful for treating diseases that are prevented by or ameliorated with Interleukin-2, Interleukin-4, or Interleukin-5 production inhibitors.