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24590-51-0

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24590-51-0 Usage

General Description

1-methoxypropan-2-yl methanesulfonate, also known as mesylate, is a chemical compound that is used as a reagent in organic synthesis. It is commonly used as a mild and selective leaving group in the substitution reactions of alcohols, phenols, and carboxylic acids. It is also utilized as a protecting group for alcohols in organic chemistry. 1-methoxypropan-2-yl methanesulfonate is a colorless liquid with a strong, unpleasant odor and is highly flammable. It is important to handle it with caution and use it in a well-ventilated area due to its potential health and safety hazards. Overall, 1-methoxypropan-2-yl methanesulfonate is a versatile chemical with a range of applications in the field of organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 24590-51-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,5,9 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 24590-51:
(7*2)+(6*4)+(5*5)+(4*9)+(3*0)+(2*5)+(1*1)=110
110 % 10 = 0
So 24590-51-0 is a valid CAS Registry Number.

24590-51-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-methoxypropan-2-yl methanesulfonate

1.2 Other means of identification

Product number -
Other names 2-Methansulfonyloxy-1-methoxy-propan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:24590-51-0 SDS

24590-51-0Relevant articles and documents

Substituted thiazole derivative and application thereof

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Paragraph 0247-0251, (2019/02/13)

The invention provides a compound represented by a general formula (I), or a stereoisomer, pharmaceutically acceptable salt, solvate, hydrate, chemically protective form or prodrug thereof. The compound has an effect of inhibiting adenosine receptor 2a (A2a), and can be used as an antagonist of the adenosine receptor 2a (A2A) for treating tumors.

Development of a High-Affinity PET Radioligand for Imaging Cannabinoid Subtype 2 Receptor

Moldovan, Rare?-Petru,Teodoro, Rodrigo,Gao, Yongjun,Deuther-Conrad, Winnie,Kranz, Mathias,Wang, Yuchuan,Kuwabara, Hiroto,Nakano, Masayoshi,Valentine, Heather,Fischer, Steffen,Pomper, Martin G.,Wong, Dean F.,Dannals, Robert F.,Brust, Peter,Horti, Andrew G.

, p. 7840 - 7855 (2016/10/12)

Cannabinoid receptors type 2 (CB2) represent a target with increasing importance for neuroimaging due to its upregulation under various pathological conditions. Encouraged by preliminary results obtained with [11C](Z)-N-(3-(2-methoxyethyl)-4,5-dimethylthiazol-2(3H)-ylidene)-2,2,3,3-tetramethyl-cyclopropanecarboxamide ([11C]A-836339, [11C]1) in a mouse model of acute neuroinflammation (induced by lipopolysaccharide, LPS), we designed a library of fluorinated analogues aiming for an [18F]-labeled radiotracer with improved CB2 binding affinity and selectivity. Compound (Z)-N-(3-(4-fluorobutyl)-4,5-dimethylthiazol-2(3H)-ylidene)-2,2,3,3-tetramethyl-cyclopropanecarboxamide (29) was selected as the ligand with the highest CB2 affinity (Ki = 0.39 nM) and selectivity over those of CB1 (factor of 1000). [18F]29 was prepared starting from the bromo precursor (53). Specific binding was shown in vitro, whereas fast metabolism was observed in vivo in CD-1 mice. Animal PET revealed a brain uptake comparable to that of [11C]1. In the LPS-treated mice, a 20-30% higher uptake in brain was found in comparison to that in nontreated mice (n = 3, P 0.05).

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

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Paragraph 00343; 00344, (2013/08/28)

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

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