24613-65-8Relevant articles and documents
Highly Selective Radical Monoreduction of Dihalides Confined to a Dynamic Supramolecular Host
Petroselli, Manuel,Rebek, Julius,Yu, Yang
supporting information, p. 3284 - 3287 (2021/02/05)
Reduction of alkyl dihalide guests (2–5 and 7) with trialkylsilanes (R3SiH) was performed in water-soluble host 1 to investigate the effects of confinement on fast radical reactions (k≥103 m?1 s?1). High selectivity (>95 %) for mono-reduced products was observed for primary and secondary dihalide guests under mild conditions. The results highlight the importance of host–guest complexation rates to modulate the product selectivity in radical reactions.