24615-03-0Relevant articles and documents
Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors
Wu, Wei-Bin,Ou, Jie-Bin,Huang, Zhi-Hong,Chen, Shuo-Bin,Ou, Tian-Miao,Tan, Jia-Heng,Li, Ding,Shen, Liu-Lan,Huang, Shi-Liang,Gu, Lian-Quan,Huang, Zhi-Shu
, p. 3339 - 3347 (2011)
A series of mansonone F (MF) derivatives were designed and synthesized. These compounds were found to be strong inhibitors for topoisomerases, with much more significant inhibition for topoisomerase II rather than topoisomerase I. The best inhibitor showe