24623-24-3 Usage
Description
6-Nitroindanone, with the molecular formula C9H7NO3, is a pale yellow solid chemical compound. It has a molecular weight of 173.16 g/mol and is known for its strong nitroaromatic characteristics. 6-NITROINDANONE is recognized for its versatile reactivity and compatibility with functional groups, making it a valuable building block in the synthesis of complex organic compounds.
Uses
Used in Organic Synthesis:
6-Nitroindanone is used as a key intermediate in the synthesis of various organic compounds due to its strong nitroaromatic characteristics and versatile reactivity.
Used in Pharmaceutical Preparation:
6-Nitroindanone is utilized as an intermediate in the preparation of pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Production:
6-NITROINDANONE is also employed in the production of agrochemicals, serving as an intermediate for the synthesis of various agricultural chemicals.
Used in Specialty Chemicals Industry:
6-Nitroindanone is used as a building block in the creation of specialty chemicals, where its functional group compatibility and reactivity are advantageous for developing unique chemical products.
In Organic Reactions:
6-Nitroindanone is used in nucleophilic additions and condensations, demonstrating its utility in various organic reactions that require the presence of a nitro group for further functionalization or transformation.
Check Digit Verification of cas no
The CAS Registry Mumber 24623-24-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,6,2 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 24623-24:
(7*2)+(6*4)+(5*6)+(4*2)+(3*3)+(2*2)+(1*4)=93
93 % 10 = 3
So 24623-24-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO3/c11-9-4-2-6-1-3-7(10(12)13)5-8(6)9/h1,3,5H,2,4H2
24623-24-3Relevant articles and documents
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Hasbun,J.A. et al.
, p. 847 - 849 (1973)
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An efficient and convenient protocol for the synthesis of 1,1-difluoro-6-nitro-2,3-dihydro-1 H -indene derivatives
Zhang, Dongfeng,Li, Peng,Lin, Ziyun,Huang, Haihong
, p. 613 - 620 (2014)
A convenient and efficient synthesis of gem-difluorinated compounds is reported. The synthetic route toward various 2-substituted and 3-substituted 1,1-difluoro-6-nitro-2,3-dihydro-1H-indene derivatives is described starting from commercially available indanone. The key gem-difluorination step is accomplished in good yield by treatment of in situ generated bromine fluoride (BrF) with a dithioketal. A plausible mechanism discussing the competition between substitution and elimination is provided to rationalize the outcome of the reactions of the 3-brominated compounds with different amines. Georg Thieme Verlag Stuttgart New York.
BRD4-JAK2 INHIBITORS
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Page/Page column 41-42, (2020/03/29)
Disclosed herein are compounds that are inhibitors of BDR4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BDR4 are also disclosed. In certain aspects, disclosed are compounds of Formula I, II, and II.
METHODS FOR MAKING QUINOLINYLDIAMINES
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Paragraph 0273-0274, (2020/03/23)
The present disclosure provides methods for making quinolinyldiamine products from quinolinyl starting materials. In addition, the quinolinyldiamines can be used as ligands or ligand precursors for catalysts, e.g. for use in olefin polymerization.
