24623-40-3

Basic information

• Product Name: 1,3-Dichloro-7-methoxyisoquinoline
• Synonyms: 1,3-Dichloro-7-methoxyisoquinoline
• CAS NO: 24623-40-3
• Molecular Formula: C₁₀H₇Cl₂NO
• Molecular Weight: 228.07468
• Mol File: 24623-40-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 367.2±37.0 °C(Predicted)
• Appearance: /
• Density: 1.384±0.06 g/cm3(Predicted)
• PKA: -1.31±0.50(Predicted)
• CAS DataBase Reference: 1,3-Dichloro-7-methoxyisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dichloro-7-methoxyisoquinoline(24623-40-3)
• EPA Substance Registry System: 1,3-Dichloro-7-methoxyisoquinoline(24623-40-3)

Safety Data

• Hazardous Substances Data: 24623-40-3(Hazardous Substances Data)

Usage

General Description

1,3-Dichloro-7-methoxyisoquinoline is a chemical compound with the molecular formula C11H8Cl2NO. It is a derivative of isoquinoline and contains two chlorine atoms and one methoxy group. 1,3-Dichloro-7-methoxyisoquinoline is used in organic synthesis and pharmaceutical research, and its structure and properties make it a valuable building block for the production of various pharmaceuticals and organic compounds. It is also used as a starting material in the synthesis of heterocyclic compounds and is a valuable tool for researchers working in the fields of medicinal chemistry and drug discovery. Additionally, 1,3-Dichloro-7-methoxyisoquinoline has been studied for its potential biological activities and may be of interest for its pharmacological effects.

Upstream product

• 24077-98-3 (Z)-2-(hydroxyimino)-6-methoxy-2,3-dihydro-1H-inden-1-one 
• 13623-25-1 6-methoxy-2,3-dihydro-1H-inden-1-one 
• 24077-98-3 2-(hydroxyimino)-6-methoxy-2,3-dihydro-1H-inden-1-one 

Downstream Products

• 1383379-89-2 3-fluoro-4-(7-methoxyisoquinolin-3-yl)benzoic acid 
• 82117-21-3 3-chloro-7-methoxyisoquinoline 
• 1383379-67-6 3-fluoro-4-(7-hydroxyisoquinolin-3-yl)benzoic acid 
• 1383379-90-5 4-(7-methoxy-4-methylisoquinolin-3-yl)benzoic acid 
• 1383379-68-7 4-(7-hydroxy-4-methylisoquinolin-3-yl)benzoic acid 
• 82117-25-7 3-chloroisoquinolin-7-ol 

Relevant articles and documents

BICYCLIC ARYL MONOBACTAM COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF BACTERIAL INFECTIONS

The present invention relates to bicyclic aryl monobactam compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein A1, L, M, W, X, Y, Z, RX and Rz are as defined herein. The present invention also relates to compositions which comprise a bicyclic aryl monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of one or more beta-lactamase inhibitor compounds.

PYRROLO[2,3-C]PYRIDINES AS IMAGING AGENTS FOR NEUROFIBRILARY TANGLES

Pyrrolopyridine compounds of formula (I) or their pharmaceutically acceptable salts are disclosed, which may be suitable for imaging tau aggregates, b-sheet aggregates, beta-amyloid aggregates or alpha- synuclein aggregates, and hence are useful in binding and imaging tau aggregates in Alzheimer's patients. More specifically, the compounds are used as tracers in positron emission tomography (PET) imaging to study tau deposits in brain in vivo to allow diagnosis of Alzheimer's disease and other neurodegenerative diseases characterized by tau pathology. Futher, the compounds are useful for measuring clinical efficacy of therapeutic agents for Alzheimer's disease and other neurodegenerative diseases characterized by tau pathology.