24628-80-6

Basic information

• Product Name: 3-methyl-5-(methylthio)-1-phenyl-1H-pyrazole-4-carbaldehyde
• Synonyms: 3-methyl-5-(methylthio)-1-phenyl-1H-pyrazole-4-carbaldehyde
• CAS NO: 24628-80-6
• Molecular Weight: 232.306
• Mol File: 24628-80-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methyl-5-(methylthio)-1-phenyl-1H-pyrazole-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-5-(methylthio)-1-phenyl-1H-pyrazole-4-carbaldehyde(24628-80-6)
• EPA Substance Registry System: 3-methyl-5-(methylthio)-1-phenyl-1H-pyrazole-4-carbaldehyde(24628-80-6)

Safety Data

• Hazardous Substances Data: 24628-80-6(Hazardous Substances Data)

Upstream product

• 868-84-8 S,S-dimethyl dithiocarbonate 
• 947-95-5 5-chloro-4-formyl-3-methyl-1-phenyl-1H-pyrazole 

Relevant articles and documents

Synthesis of novel β-aryl-β-(methylthio)acroleins via Vilsmeier-Haack protocol as potential 1,3-dielectrophilic three-carbon building blocks

A new general route for the synthesis of novel β-aryl-β- (methylthio)acroleins, a class of stable potential 1,3-dielectrophilic synthons, has been reported. The overall protocol involves treatment of either β-chloroacroleins or their precursor iminium salts (generated in situ from the corresponding active methylene ketones under Vilsmeier-Haack reaction conditions) with S,S-dimethyldithiocarbonates (DDC)/aqueous KOH in either a one-pot or two-step process. The dimethyldithiocarbonate (DDC)/30% aqueous KOH has been shown to be an excellent source of methylthiolate anion.