24637-27-2

Basic information

• Product Name: 1-Piperazineaceticacid,hydrazide(8CI)
• Synonyms: 1-Piperazineaceticacid,hydrazide(8CI);2-PIPERAZIN-1-YLACETOHYDRAZIDE
• CAS NO: 24637-27-2
• Molecular Formula: C6 H14 N4 O
• Molecular Weight: 158.2
• Product Categories: PIPERIDINE
• Mol File: 24637-27-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Piperazineaceticacid,hydrazide(8CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazineaceticacid,hydrazide(8CI)(24637-27-2)
• EPA Substance Registry System: 1-Piperazineaceticacid,hydrazide(8CI)(24637-27-2)

Safety Data

• Hazardous Substances Data: 24637-27-2(Hazardous Substances Data)

Usage

Appearance

white crystalline powder
Known for hydrazine-like properties
Inhibits the formation of advanced glycation end products (AGEs)
Potential use in the treatment of tuberculosis

Specific content

Used in various chemical reactions and processes
Used in the synthesis of various pharmaceutical and organic compounds
Linked to various diseases such as diabetes and Alzheimer's

Upstream product

• 40004-08-8 1-(Ethoxycarbonylmethyl)piperazine 

Downstream Products

• 1075725-64-2 N′-[[2-hydroxy-3-(2-propenyl)phenyl]methylene]-4-[(4-fluorophenyl)methyl]-1-piperazineacetohydrazide 
• 1075725-61-9 N'-(3-allyl-2-hydroxybenzylidene)-2-(4-(pyridin-2-ylmethyl)piperazin-1-yl)acetohydrazide 
• 1075725-62-0 N'-(3-allyl-2-hydroxybenzylidene)-2-(4-(pyridin-3-ylmethyl)piperazin-1-yl)acetohydrazide 
• 1075725-63-1 N'-(3-allyl-2-hydroxybenzylidene)-2-(4-(pyridin-4-ylmethyl)piperazin-1-yl)acetohydrazide 
• 1238608-21-3 C₁₉H₂₂N₄O 

Relevant articles and documents

Rhodamine B piperazinoacetohydrazine: A water-soluble spectroscopic reagent for pyruvic acid labeling

A new water-soluble reagent, rhodamine B piperazinoacetohydrazine (RBPH), with improved spectroscopic and reaction properties, has been developed and characterized for pyruvic acid labeling. The reagent RBPH is designed and synthesized by using rhodamine B as a spectroscopic unit, and hydrazine as a carbonyl-specific labeling unit; the two units are connected by a well-chosen linker of piperazine, which prohibits the formation of the nonfluorescent spirocyclic structure of rho-damine B, thereby keeping the spectroscopic response of the reagent in a stable state. Such a design enables RBPH not only to maintain its excellent spectroscopic properties over a wide pH range, but also to exist as a stable cation with high water solubility. Moreover, the hydrazino group of RBPH is expected to react selectively with carbonyl compounds under mild conditions through the rapid formation of hydrazones. These important features make RBPH of great potential use in the labeling of aldehydes or ketones in various biosystems, and such an application of RBPH as a precolumn derivatizing reagent has been successfully demonstrated on the analysis of pyruvic acid in human serum by high-performance liquid chromatography with common UV/Vis detection.