2465-91-0Relevant articles and documents
Highly conductive electrolytes derived from nitrile solvents
Ma, Qiang,Mandal, Braja K.
, p. A1276 - A1281 (2015)
A series of new low molecular weight nitrile solvents has been designed and synthesized for secondary lithium battery electrolytes. Lithium bis(trifluoromethylsulonyl) imide (LiTFSI) salt concentration and temperature dependent ionic conductivity, electrochemical stability and thermal properties have been studied. The best ionic conductivity, 12.9 × 10-3 S/cm at 25°C, was observed with 1.60M LiTFSI in 2,2-bis(hydroxymethyl)-1,3-propanedi-2-ethylcyano solvent. Both electrolytes and neat solvents displayed freezing point below -80°C.
Preparation and application of three-branch RGD modified brain glioma targeting lipid material
-
Paragraph 0033, (2021/11/03)
The invention discloses a three-branch RGD-modified glioma targeting lipid material which is used for targeted delivery of brain glioma treatment drugs. One end of the novel lipid material is connected with cholesterol extending through polyethylene glycol, and the other end of the novel lipid material is connected with RGD peptide with brain glioma targeting function, and the novel lipid material can be used for integrin receptor α which is highly expressed on the surface of brain capillary endothelial cells and brain glioma cells. v β3 The affinity between the brain glioma is achieved through the affinity between the brain glioma, and the effective concentration of the therapeutic drug to the brain tumor is improved. The novel lipid lipid material can be used for liposome. The prepared paclitaxel liposome has obvious brain targeting property and tumor targeting property, and has wide application prospects.
NUCLEOPHILE-TRIGGERED DEGRADBLE MATERIALS AND METHODS OF MAKING AND USING THE SAME
-
Paragraph 00130, (2016/06/28)
Disclosed herein are degradable materials comprising the reaction product of an oxanorbomadiene crosslinker or derivative thereof and a multivalent nucleophile-terminated compound, wherein the reaction product is a degradable elastic solid capable of entraining cargo. Also disclosed herein are degradable materials comprising a polymeric and hyperbranched crosslinked material made with oxanorbomadiene linkage that can be activated for cleavage at a predetermined rate by addition of a nucleophile. Also disclosed herein are methods of making and using the same.
Antibodies that inhibit metalloproteins
-
Page/Page column 28, (2016/01/09)
An antibody is disclosed which comprises an antigen recognition region which comprises six CDR amino acid sequences selected from the group consisting of SEQ ID NOs: 4-15. Uses thereof are also disclosed.