246516-49-4

Upstream product

• 2212-75-1 N₂-[(benzyloxy)carbonyl]-L-lysine 
• 246516-48-3 3-carboxypropyl O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->4)-O-2-acetamido-3,6-di-O-acetyl-2-deoxy-β-D-glucopyranoside 

Downstream Products

• 246516-50-7 Z-Lys[3-carbamidopropyl O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->4)-O-2-acetamido-3,6-di-O-acetyl-2-deoxy-β-D-glucopyranoside]-Gly-OBn 

Relevant academic research and scientific papers

Specific crosslinking of cell adhesive molecules by heterobifunctional glycopeptide synthesised on the basis of chemoenzymatic strategy

Heterobifunctional glycopeptide 1 composed of Neu5Acα-(2→3)Galβ(1→4)[Fucα(1→3)]GlcNAc (sialyl Lewis(x)) and Lys-Gly-Arg-Gly-Asp-Ser (KGRGDS) having specific activity to bind concurrently with two different types of cell adhesive molecules such as selectin

Heterobifunctional ligands: Practical chemoenzymatic synthesis of a cell adhesive glycopeptide that interacts with both selectins and integrins

An efficient and practical synthesis of cell adhesive glycopeptides exhibiting unique properties as a novel type of modulator of cellular recognition is described. A nonnatural glycopeptide 1 composed of sialyl Lewis x and Lys-Gly-Arg-Gly-Asp-Ser that int