246530-08-5Relevant articles and documents
Process for the Preparation of Idnanones
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Paragraph 0101; 0102, (2019/09/06)
A process of forming compounds of formula I comprising the steps of addition of an amino compound H2NR to a compound of formula (II) followed by cyclization, isomerization and hydrolysis.
Concise total synthesis of (±)-cephalotaxine via a transannulation strategy: Development of a facile reductive oxy-Nazarov cyclization
Li, Wei-Dong Z.,Duo, Wei-Guo,Zhuang, Cheng-Han
supporting information; experimental part, p. 3538 - 3541 (2011/08/22)
A concise total synthesis of (±)-cephalotaxine (1) has been achieved from dioxolanone derivative 15 via a transannulation strategy. The key transformation is a facile reductive oxy-Nazarov cyclization as illustrated above, involving presumably a tethered 1,2-oxidopentadienyl cation species 7a or 7b, which represents a new variant of the oxy-Nazarov cyclization and constitutes an effective, regio- and stereospecific 5-hydroxy cyclopentenone annulation protocol under mild hydride reduction conditions.