246530-89-2Relevant academic research and scientific papers
Synthesis and biological evaluation of dianhydrohexitol integrin antagonists
Osterkamp, Frank,Wehlan, Hermut,Koert, Ulrich,Wiesner, Matthias,Raddatz, Peter,Goodman, Simon L.
, p. 10713 - 10734 (2007/10/03)
The synthesis of a series of RGD mimetics is described. All compounds have a 1.4:3.6dianhydrohexitol core. a variable linker to a guanidino group, and a serine ether to mimic the carboxylic acid. Two types of linkers were combined with 1.4:3.6-dianhydro-D
