246854-75-1Relevant academic research and scientific papers
Cubanes in medicinal chemistry: Synthesis of functionalized building blocks
Wlochal, Joanna,Davies, Robert D. M.,Burton, Jonathan
, p. 4094 - 4097 (2014)
A collection of novel, pharmaceutically relevant cubane-containing molecules has been prepared from the commercially available cubane-1,4- dimethylester. A range of synthetic methods have been applied to prepare these cubane building blocks with one or two functional handles to allow easy incorporation into existing medicinal chemistry programs.
Indoleamine 2,3-dioxygenase inhibitor
-
, (2020/12/30)
The invention provides a novel compound capable of inhibiting activity of indoleamine 2,3-dioxygenase (IDO), a pharmaceutical composition containing the compound, a preparation method of the compoundand application of the compound in preparation of drugs for treating proliferative diseases, infectious diseases, immune-related diseases and/or inflammatory diseases.
