246865-92-9Relevant academic research and scientific papers
Synthesis of the sialyl Lewis X epitope attached to glycolipids with different core structures and their selectin-binding characteristics in a dynamic test system
Gege, Christian,Vogel, Jan,Bendas, Gerd,Rothe, Ulrich,Schmidt, Richard R.
, p. 111 - 122 (2007/10/03)
Sialyl Lewis X (sLe(X))/selectin-mediated leukocyte rolling along endothelial cells has recently gained wide interest. In this paper the influence of the spacer length of laterally clustered neoglycolipids 1a-d on cell rolling in a dynamic test system is
Syntheses of α-dystroglycan derived sialylated glycosyl amino acids carrying a novel mannosyl serine/threonine linkage
Seifert, Joachim,Ogawa, Tomoya,Ito, Yukishige
, p. 6803 - 6807 (2007/10/03)
An efficient access to the Fmoc protected glycosyl amino acids 20a-d which correspond to the unique sequence NeuNAc-α-(2,3)-Gal-β-(1,4)-GlcNAc-β-(1,2)-Man-α-Ser/Thr recently found in laminin-binding protein α-dystroglycan, is described. Tetrasaccharide donor 18 was constructed from monosaccharide blocks 2, 3, 8 and 9 and coupled with Ser/Thr derivatives 19a-d. Resultant glycosyl amino acid 20d was completely deprotected into 1a.
