246869-66-9

Upstream product

• 210420-48-7 trans-N-Boc-3-phenyl-proline 
• 246869-32-9 3-Phenyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 37089-77-3 3,3-diphenylpropanoyl chloride 
• 111934-23-7 MeNH-L-Lys(ε-Cbz)-CO2Me 

Downstream Products

• 246869-68-1 ((S)-5-Benzylcarbamoyl-5-{[(2S,3R)-1-(3,3-diphenyl-propionyl)-3-phenyl-pyrrolidine-2-carbonyl]-methyl-amino}-pentyl)-carbamic acid benzyl ester 
• 246869-67-0 (S)-6-Benzyloxycarbonylamino-2-{[(2S,3R)-1-(3,3-diphenyl-propionyl)-3-phenyl-pyrrolidine-2-carbonyl]-methyl-amino}-hexanoic acid 

Relevant academic research and scientific papers

Synthesis of novel proline and γ-lactam derivatives as non-peptide mimics of Somatostatin/Sandostatin

Original proline or γ-lactam derivatives bearing either an aryl group such as a phenyl or a 3-indolyl in position 3 of the proline moiety or on the 3-methyl chain of the γ-lactam skeleton were prepared as non-peptide mimics of Somatostatin/Sandostatin.