247019-80-3

Basic information

• Product Name: 4-(1-ethoxy-ethoxy)-1-(4-phenylsulfanyl-tetrahydro-pyran-4-yl)-butan-1-ol
• Synonyms: 4-(1-ethoxy-ethoxy)-1-(4-phenylsulfanyl-tetrahydro-pyran-4-yl)-butan-1-ol
• CAS NO: 247019-80-3
• Molecular Weight: 354.511
• Mol File: 247019-80-3.mol

Chemical Properties

• CAS DataBase Reference: 4-(1-ethoxy-ethoxy)-1-(4-phenylsulfanyl-tetrahydro-pyran-4-yl)-butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-ethoxy-ethoxy)-1-(4-phenylsulfanyl-tetrahydro-pyran-4-yl)-butan-1-ol(247019-80-3)
• EPA Substance Registry System: 4-(1-ethoxy-ethoxy)-1-(4-phenylsulfanyl-tetrahydro-pyran-4-yl)-butan-1-ol(247019-80-3)

Safety Data

• Hazardous Substances Data: 247019-80-3(Hazardous Substances Data)

Upstream product

• 37494-03-4 3-(1-ethoxyethoxy)propyllithium 
• 179088-48-3 4-(Phenylsulfanyl)-3,4,5,6-tetrahydropyran-4(2H)-carboxaldehyde 

Downstream Products

• 247019-89-2 4-(4-phenylsulfanyl-tetrahydro-pyran-4-yl)-[1,3,2]dioxathiepane 2-oxide 
• 247019-86-9 4-phenylsulfanyl-4-(tetrahydro-furan-2-yl)-tetrahydro-pyran 
• 247019-82-5 1-(4-phenylsulfanyl-tetrahydro-pyran-4-yl)-butane-1,4-diol 

Relevant articles and documents

Kinetic and thermodynamic control in the synthesis of tetrahydro-pyrans and -furans from 1,4-diols by stereospecific phenylsulfanyl (PhS) migration: Competition between exo and endo transition states and between [1,2] and [1,4] sulfanyl participation

The factors controlling the cyclisation of 1,4-diols with PhS migration to give THPs rather than THFs are reassessed. Furthermore we provide evidence for a competition between [1,2] and [1,4] sulfanyl participation and cyclisation onto a five membered cyclic sulfonium salt.