247050-08-4

Upstream product

• 501-53-1 benzyl chloroformate 
• 641617-08-5 (2R/S,4S)-4-[(N-benzyloxycarbonyl)aminomethyl]-1,3,2λ4-dioxathiolane-2-one 

Downstream Products

• 565234-15-3 benzyl (2S,3R,6S)-6-(bromomethyl)-2,3-dimethoxy-2,3-dimethylmorpholine-4-carboxylate 
• 2448-45-5 Cbz-D-Phe 
• 127474-54-8 (R)-2-(benzyloxycarbonylamino)pent-4-enoic acid 
• 565234-17-5 benzyl (2S,3R)-2,3-dimethoxy-2,3-dimethyl-6-oxomorpholine-4-carboxylate 
• 565234-16-4 (2S,3R)-2,3-Dimethoxy-2,3-dimethyl-6-methylene-morpholine-4-carboxylic acid benzyl ester 
• 565234-18-6 benzyl (2S,3R,5R)-5-allyl-2,3-dimethoxy-2,3-dimethyl-6-oxomorpholine-4-carboxylate 
• 565234-20-0 benzyl (2S,3R,5R)-5-benzyl-2,3-dimethoxy-2,3-dimethyl-6-oxomorpholine-4-carboxylate 
• 763101-44-6 benzyl (2S,3R,5R)-2,3-dimethoxy-2,3-dimethyl-5-(2-methylprop-2-enyl)-6-oxomorpholine-4-carboxylate 

Relevant academic research and scientific papers

PROCESS FOR PREPARATION OF OPTICALLY ACTIVE 1-SUBSTITUTED AMINO-2,3-EPOXYPROPANES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND PROCESS FOR PREPARATION OF THE INTERMEDIATES

The present invention provides an industrial process for effectively and advantageously preparing optically active 1-substituted amino-2,3-epoxypropanes useful as intermediates for preparing agricultural chemicals and medical products from optically activ

The preparation and alkylation of a butanedione-derived chiral glycine equivalent and its use for the synthesis of α-amino acids and α,α-disubstituted amino acids

A benzyloxycarbonyl protected glycine equivalent 2 has been prepared in enantiopure form and has been used in the synthesis of both α-substituted amino acids and α,α-disubstituted amino acids. The process involved deprotonation to form the corresponding enolates which underwent stereoselective alkylation with various electrophiles and upon hydrolysis gave the corresponding amino acid derivatives as enantiomerically pure products.

A 2,3-butanedione protected chiral glycine equivalent--a new building block for the stereoselective synthesis of enantiopure N-protected alpha-amino acids.

A new chiral glycine equivalent 7 has been synthesised from glycidol using a chiral memory protocol, and its use in the synthesis of N-Z protected alpha-amino acids was demonstrated in a series of diasteroselective lithium enolate alkylation reactions and subsequent acid hydrolyses.

Process for preparing chiral (s)-2,3-disubstituted-1-propylamine derivatives

A process for the preparation of chiral (S)-2,3-disubstituted-1-propylamine derivatives, in which a carbonyl group of (S) 3,4-disubstituted-1-butanecarbonyl derivatives is converted to an amine group, and the conversion reaction is performed through Curti