247075-77-0Relevant academic research and scientific papers
Glycosylation of fluoroquinolones through direct and oxygenated polymethylene linkages as a sugar-mediated active transport system for antimicrobials
Jung, Michael E.,Yang, Eric C.,Vu, Binh T.,Kiankarimi, Mehrak,Spyrou, Emmanouil,Kaunitz, Jon
, p. 3899 - 3909 (1999)
We report herein the synthesis and biological testing of several glycosylated derivatives of some fluoroquinolone antibiotics. In particular, we have prepared several glycosylated derivatives of ciprofloxacin (2) in which the carbohydrate units are linked
