247078-58-6

Basic information

• Product Name: Isopropyl (1S)-(+)-10-CaMphorsulfate
• Synonyms: Isopropyl (1S)-(+)-10-CaMphorsulfate;isopropyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
• CAS NO: 247078-58-6
• Molecular Formula: C₁₃H₂₂O₄S
• Molecular Weight: 274.37638
• Product Categories: Metabolites & Impurities
• Mol File: 247078-58-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 401.1±18.0 °C(Predicted)
• Appearance: /
• Density: 1.176±0.06 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: Isopropyl (1S)-(+)-10-CaMphorsulfate(CAS DataBase Reference)
• NIST Chemistry Reference: Isopropyl (1S)-(+)-10-CaMphorsulfate(247078-58-6)
• EPA Substance Registry System: Isopropyl (1S)-(+)-10-CaMphorsulfate(247078-58-6)

Safety Data

• Hazardous Substances Data: 247078-58-6(Hazardous Substances Data)

Usage

Uses

An Impurity from the synthesis of Frovatriptan Succinate (F768500).

Upstream product

• 21286-54-4 Camphorsulfonyl chloride 
• 67-63-0 isopropyl alcohol 

Relevant articles and documents

Stereocontrolled synthesis of novel enantiomerically pure sulfides and selenides from (+)-camphor and (+)-camphor-10-sulfonyl chloride

Synthetic approaches to novel enantiomerically pure sulfides and selenides derived from (+)-camphor and (+)-camphor-10-sulfonate esters are described. Lewis acid mediated hemiacetal formation between a camphor- derived ketone and a thiol or selenol, and subsequent in situ reduction using triethylsilane selectively gives the exo-sulfide or -selenide in moderate overall yields. The initial sulfonate ester products can be converted into the corresponding sulfones by subsequent treatment with Grignard or organolithium reagents.