247083-12-1

Basic information

• Product Name: 1H-Benzimidazole, 4-(1-piperazinyl)-1-(triphenylmethyl)-
• CAS NO: 247083-12-1
• Molecular Formula: C30H28N4
• Molecular Weight: 444.579
• Mol File: 247083-12-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Benzimidazole, 4-(1-piperazinyl)-1-(triphenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole, 4-(1-piperazinyl)-1-(triphenylmethyl)-(247083-12-1)
• EPA Substance Registry System: 1H-Benzimidazole, 4-(1-piperazinyl)-1-(triphenylmethyl)-(247083-12-1)

Safety Data

• Hazardous Substances Data: 247083-12-1(Hazardous Substances Data)

Upstream product

• 83741-35-9 4-bromo-1H-benzo[d]imidazole 
• 76-83-5 trityl chloride 
• 110-85-0 piperazine 
• 247083-08-5 4-bromo-1-trityl-1H-benzo[d]imidazole 

Downstream Products

• 1146734-17-9 1-{5-[4-(1-trityl(1H)-benzimidazol-4-yl)piperazin-1-yl]pentyl}-1,3-dihydro-2H-indol-2-one 
• 770719-42-1 2-[[4-(1-tritylbenzimidazol-4-yl)piperazin-1-yl]methyl]benzimidazole-4-carboxylic acid 
• 247083-16-5 2-[4-[4-(1-tritylbenzimidazol-4-yl)piperazin-1-yl]butyl]-1,3-dioxoperhydropyrrolo[1,2-c]imidazole 

Relevant articles and documents

COMPOUNDS FOR BINDING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9)

The present disclosure relates to novel compounds, methods, and compositions capable of binding to PCSK9, thereby modulating PCSK9 proprotein convertase enzyme activity. The compounds of the disclosure include compounds Formula (I).

Synthesis of new (benzimidazolyl)piperazines with affinity for the 5- HT(1A) receptor via Pd(0) amination of bromobenzimidazoles

The synthesis of a new family of (benzimidazolyl)piperazines has been developed through Pd(0) mediated amination of 4- and 6-bromobenzimidazole derivatives. Preliminary studies showed that some of these compounds are potent 5-HT(1A) receptor ligands.