24730-10-7

Basic information

• Product Name: DIHYDROERGOCRISTINE MESYLATE
• Synonyms: (5’-alpha,10-alpha)-nylmethyl)monomethanesulfonate(salt);9,10-dihydro-ergocristinmonomethanesulfonate(salt);dihydroergocristinmesilat;ergotamane-3’,6’,18-trione,9,10-dihydro-12’-hydroxy-2’-(1-methylethyl)-5’-(phe;DIHYDROERGOCRISTINE MESYLATE;DIHYDROERGOCRISTINE METHANESULFONATE;DIHYDROERGOCRYSTINE METHANESULFONATE SALT;(5'A,10A)-9,10-DIHYDRO-12'-HYDROXY-2'-(1-METHYLETHYL)-5'-(PHENYLMETHYL)-ERGOTAMAN-3',6',18-TRIONE MESYLATE
• CAS NO: 24730-10-7
• Molecular Formula: CH₄O₃S*C₃₅H₄₁N₅O₅
• Molecular Weight: 707.84
• EINECS: 246-434-6
• Product Categories: Organics;DID - DINDrugs of Abuse;ErgotamineForensic and Veterinary Standards;AlkaloidsAlphabetic;Chemical Structure;D;Drugs of Abuse;Drugs&Metabolites;Neat Compounds;Serotonin receptor
• Mol File: 24730-10-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 210 °C
• Boiling Point: 899.3 °C at 760 mmHg
• Flash Point: 497.7 °C
• Appearance: /
• Vapor Pressure: 8.49E-35mmHg at 25°C
• Storage Temp.: Store at RT
• Solubility: H2O: 10 mg/mL
• CAS DataBase Reference: DIHYDROERGOCRISTINE MESYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIHYDROERGOCRISTINE MESYLATE(24730-10-7)
• EPA Substance Registry System: DIHYDROERGOCRISTINE MESYLATE(24730-10-7)

Safety Data

• RIDADR: UN 1544 6.1/PG 2
• WGK Germany: 2
• RTECS: KE7600000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 24730-10-7(Hazardous Substances Data)

Usage

Chemical Properties

White or almost white, fine crystalline powder.

Uses

Different sources of media describe the Uses of 24730-10-7 differently. You can refer to the following data:
1. 5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors
2. Alpha receptor blocking
3. 4,10-Dihydroergocristine Methanesulfonate is an nontoxic and well tolerated drug that exerts agonistic and antagonistic activity on dopaminergic and adrenergic receptors. 4,10-Dihydroergocristine Meth anesulfonate is known to exhibit protective properties to the brain against metabolic effects of ischemia by acting at a cellular level.

Definition

ChEBI: The methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. It is also a component of ergoloid mesylat (codergocrine mesilate), a mixture of ergot alkaloid derivatives that is used as a vasodilator and has shown mild benefits in the treatment of vascular dementia.

Biological Activity

5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors.

InChI:InChI=1/C35H41N5O5.CH4O3S/c1-20(2)34(37-31(41)23-16-25-24-11-7-12-26-30(24)22(18-36-26)17-27(25)38(3)19-23)33(43)40-28(15-21-9-5-4-6-10-21)32(42)39-14-8-13-29(39)35(40,44)45-34;1-5(2,3)4/h4-7,9-12,18,20,23,25,27-29,36,44H,8,13-17,19H2,1-3H3,(H,37,41);1H3,(H,2,3,4)/t23-,25-,27-,28+,29+,34-,35+;/m1./s1

Downstream Products

• 17479-19-5 dihydroergocristine