24738-21-4

Upstream product

• 34724-16-8 1,2;3,3'-di-O-isopropylidene-3-C-(hydroxymethyl)-α-D-erythrofuranose 
• 14048-35-2 (-)-(3aR,6S,6aR)-6-hydroxymethyl-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 42933-13-1 (2S,3S)-2-methylbutane-1,2,3,4-tetraol 
• 93836-33-0 1,2,3,4-tetra-O-benzoyl-3-C-methyl-L-threitol 

Relevant academic research and scientific papers

Synthesis of 3-C-(hydroxymethyl)erythritol and 3-C-methylerythritol.

3-C-(Hydroxymethyl)erythritol was prepared from 3-C-(hydroxymethyl)-2,3-O-isopropylidene-D-erythro-tetrofuranose (4) by hydrolysis followed by reduction, or by reduction followed by hydrolysis. Monotosylation of 4, followed by reduction with lithium aluminum hydride and hydrolysis, afforded 3-C-methylerythritol.