24738-84-9Relevant academic research and scientific papers
REACTIVITE COMPAREE DES ISOMERES IMINE ET ENAMINE SILICIES: SYNTHESE ENANTIOSELECTIVE DE L'(OXO-2 CYCLOHEXYL)-3 PROPIONATE DE METHYLE
Fourtinon, Michel,Jeso, Bernard de,Pommier, Jean-Claude
, p. 239 - 246 (2007/10/02)
The isomerisation process between SiMe3-substituted enamines and imines (N-SiC-Si) is so slow that each isomer is able to react independently.The silicon-substituted (S)-phenylethylamine derivative adds to methyl acrylate and forms, upon hydrolysis, methyl (S)-3-(2-oxocyclohexyl)propane carboxylate.The tautomeric imine leads to the (R)-enantiomer.Surprisingly, in the presence of a Lewis acid, the ring-containing organosilicon-substituted derivatives show lower stereoselectivity than the corresponding tin compounds.
TRIMETHYLCHOLOROSILANE INDUCED RING OPENING OF 2-ALKYLOXAZOLIDINES TO ENAMINE DERIVATIVES
Ito, Yoshihiko,Sawamura, Masaya,Kominami, Kazuhiko,Saegusa, Takeo
, p. 5303 - 5306 (2007/10/02)
2-Alkyloxazolidines (5) were ring-opened by trimethylchlorosilane with N,N-diisopropylamine to give N--enamines (6).A MgCl2 promoted Michael reaction of chiral enamines thus prepared was achieved with asymmetric induction.
Asymmetric Michael Additions. Stereoselective Alkylations of the (R)- and (S)-Enamine from Cyclohexanone and 2-(Methoxymethyl)pyrrolidine by Methyl α-(Methoxycarbonyl)cinnamates
Blarer, Stefan J.,Seebach, Dieter
, p. 2250 - 2260 (2007/10/02)
Alkylation of (2S)-1-(1-cyclohexen-1-yl)-2-(methoxymethyl)pyrrolidine ((S)-1, enamine from cyclohexanone and 2-(methoxymethyl)pyrrolidine) by the Knoevenagel condensation products 4 of aromatic aldehydes yields 35-76percent of Michael adducts (1 + 4 -> ->
