Welcome to LookChem.com Sign In|Join Free

CAS

  • or

24744-59-0

Post Buying Request

24744-59-0 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

24744-59-0 Usage

General Description

Ethyl (3,5-dibromo-4-hydroxyphenyl)acetate is a chemical compound with the molecular formula C10H10Br2O4. It is a derivative of ethyl acetate and contains bromine and hydroxyphenyl functional groups. ethyl (3,5-dibromo-4-hydroxyphenyl)acetate is used in various applications, including as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential antimicrobial and antioxidant properties. However, it is important to handle this chemical with care, as it may have hazardous effects on human health and the environment. Overall, ethyl (3,5-dibromo-4-hydroxyphenyl)acetate is a versatile compound with potential industrial and biological applications.

Check Digit Verification of cas no

The CAS Registry Mumber 24744-59-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,7,4 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 24744-59:
(7*2)+(6*4)+(5*7)+(4*4)+(3*4)+(2*5)+(1*9)=120
120 % 10 = 0
So 24744-59-0 is a valid CAS Registry Number.

24744-59-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-(3,5-dibromo-4-hydroxyphenyl)acetate

1.2 Other means of identification

Product number -
Other names 3,5-dibromo-4-hydroxyphenylacetic acid ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:24744-59-0 SDS

24744-59-0Relevant articles and documents

Halogenation of 4-hydroxy/amino-3-methoxyphenyl acetamide TRPV1 agonists showed enhanced antagonism to capsaicin

Kang, Dong Wook,Kim, Yong Soo,Lim, Kwang Su,Kim, Myeong Seop,Pearce, Larry V.,Pavlyukovets, Vladimir A.,Tao, Andy K.,Lang-Kuhs, Krystle A.,Blumberg, Peter M.,Lee, Jeewoo

experimental part, p. 8092 - 8105 (2011/01/13)

As an extension of our analysis of the effect of halogenation on thiourea TRPV1 agonists, we have now modified selected 4-hydroxy(or 4-amino)-3- methoxyphenyl acetamide TRPV1 agonists by 5- or 6-halogenation on the aromatic A-region and evaluated them for potency for TRPV1 binding and regulation and for their pattern of agonism/antagonism (efficacy). Halogenation shifted the functional activity at TRPV1 toward antagonism with a greater extent of antagonism as the size of the halogen increased (I > Br > Cl), as previously observed for the thiourea series. The extent of antagonism was greater for halogenation at the 5-position than at the 6-position, in contrast to SAR for the thiourea series. In this series, compounds 55 and 75 showed the most potent antagonism, with Ki (ant) = 2.77 and 2.19 nM, respectively, on rTRPV1 expressed in Chinese hamster ovary cells. The compounds were thus ca. 40-60-fold more potent than 6′-iodononivamide.

4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents

-

, (2008/06/13)

Compounds of general formula (I) STR1 wherein R 1 is (CH 2) n ((CHNR 7 R 8) m C(O)R 9 ; n=1-3; and m=0 or 1;R 3 and R 5 are independently Cl, Br, I, or CH 3 ;R 7 and R 8 are independently H or (C 1 -C 4)alkyl;R 9 is OH, (C 1 -C 4)alkoxy, or NR 7 R 8 ;R 31 is H, Cl, Br, I, (C 1 -C 4)alkyl, (C 4 -C 6)cycloalkyl, (C 1 -C 4)haloalkyl, (C 4 -C 6)halocycloalkyl, or --CH(R 10)Ar where Ar is selected from 5-hydroxypyrid-2-yl, 6-hydroxypyrid-3-yl, 6-hydroxypyridazin-3-yl, 6-methoxypyridazin-3-yl, 6-hydroxypyridazin-3-yl N-oxide, and 6-methoxypyridazin-3-yl N-oxide and R 10 is H or (C 1 -C 4)alkyl;R 41 is OH or a bioprecursor thereof; and the pharmaceutically acceptable salts thereof; are structural analogs of the thyroid hormones T 3 and T 4 and exhibit selective thyromimetic activity. Pharmaceutical compositions of the novel compounds and their use for the treatment of mammalian cholesteremia are provided.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 24744-59-0