2475-82-3

Usage

Uses

Used in Pharmaceutical Industry:
2-amino-5-ethylbenzoic acid serves as an active pharmaceutical ingredient due to its anti-inflammatory and analgesic properties, making it valuable for the development of medications aimed at treating pain and inflammation.
Used in Dye Production:
In the dye industry, 2-amino-5-ethylbenzoic acid is used as a key intermediate in the synthesis of various dyes, contributing to the coloration and stability of these products.
Used in Organic Synthesis:
As a building block in organic synthesis, 2-amino-5-ethylbenzoic acid is employed in the preparation of a wide range of organic compounds, showcasing its utility in creating complex molecules for various applications.
Used as a Precursor in Agricultural Products:
2-amino-5-ethylbenzoic acid also acts as a precursor in the production of certain agricultural products, potentially enhancing crop yields or providing protection against pests and diseases.
Used in Research and Development:
In the scientific community, 2-amino-5-ethylbenzoic acid is utilized in research for its potential therapeutic applications, including further exploration of its anti-inflammatory and analgesic effects, as well as its role in the synthesis of new pharmaceutical compounds.

InChI:InChI=1/C9H11NO2/c1-2-6-3-4-8(10)7(5-6)9(11)12/h3-5H,2,10H2,1H3,(H,11,12)

Upstream product

• 96202-56-1 5-ethyl-1H-indole-2,3-dione 
• 589-16-2 4-aminoethylbenzene 

Downstream Products

• 491876-89-2 (6-ethyl-4-oxo-3,4-dihydro-quinazolin-2-yl)-acetonitrile 
• 2475-78-7 ethyl 2-amino-5-ethylbenzoate 
• 19138-40-0 Bis-(4-ethyl-2-carboxyphenyl)disulfid 

Relevant academic research and scientific papers

Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor

The receptor tyrosine kinase Axl plays important roles in promoting cancer progression, metastasis, and drug resistance and has been identified as a promising target for anticancer therapeutics. We used molecular modeling-assisted structural optimization starting with the low micromolar potency compound 9 to discover compound 13c, a highly potent and orally bioavailable Axl inhibitor. Selectivity profiling showed that 13c could inhibit the well-known oncogenic kinase Met with equal potency to its inhibition of Axl superfamily kinases. Compound 13c significantly inhibited cellular Axl and Met signaling, suppressed Axl- and Met-driven cell proliferation, and restrained Gas6/Axl-mediated cancer cell migration or invasion. Furthermore, 13c exhibited significant antitumor efficacy in Axl-driven and Met-driven tumor xenograft models, causing tumor stasis or regression at well-tolerated doses. All these favorable data make 13c a promising therapeutic candidate for cancer treatment.

Containing 2 - methyl - 4 - [...] - 6 - yl of the chalcone analogs and its preparation and use

The invention discloses a chalcone analogue containing 2-methyl-4-oxo-quinazoline-6-base, shown in a general formula (I), wherein the definitions of Ar1 and Ar2 are shown in the description. Besides, the invention further discloses a preparation method an

Organic field-effect transistors based on solution-processible dibenzotetrathiafulvalene derivatives

Organic field-effect transistors based on alkyl-substituted dibenzotetrathiafulvalenes (DBTTF) are fabricated by solution process. The molecules with butyl or longer alkyl groups are standing perpendicular to the substrates in the thin films, and the tran

Sulfonamides having antiangiogenic and anticancer activity

Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating

Sulfonamides having antiangiogenic and anticancer activity

Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.

Sulfonamides having antiangiogenic and anticancer activity

Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.

1H-IMIDAZO[4,5-c]QUINOLINE DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

The invention relates to the use of imidazoquinolines and salts thereof in the treatment of protein kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases, imidazoquinolines for use in the treatment of protein kinase dependent diseases, a method of treatment against said diseases, comprising administering the imidazoloquinolines to a warm-blooded animal, especially a human, pharmaceutical preparations comprising an imidazoquinoline, especially for the treatment of a protein kinase dependent disease, novel imidazoquinolines, and a process for the preparation of the novel imidazoquinolines.