24752-26-9

Upstream product

• 106-47-8 4-chloro-aniline 
• 4887-95-0 2,5-dichloro-1H-benzimidazole 
• 14223-48-4 p-chlorophenyl isoselenocyanate 
• 95-83-0 4-Chloro-1,2-phenylenediamine 

Relevant academic research and scientific papers

Novel synthesis of 2-aminobenzimidazoles from isoselenocyanates

An efficient one-pot procedure for the synthesis of 2-aminobenzimidazoles from isoselenocyanates and various substituted diamines is described. Precipitation of elemental selenium from the reaction mixture greatly simplifies the purification procedure and also allows it to be re-used for preparation of isoseleno?cyanates. A possible mechanism for the formation of 2-aminobenzimidazoles is proposed. Georg Thieme Verlag Stuttgart - New York.

Synthesis and antimicrobial activity of some new anilino benzimidazoles

A series of 2-(anilino or 2,6-dichloroanilino)- 1,5(6)-disubstituted-1H-benzimidazoles (1-13) were prepared by reaction of several 2-chloro- or 2-chloromethyl-1H-benzimidazoles with aniline derivatives. The prepared compounds were screened for their in vitro antibacterial and antifungal activities. Compounds 2, 8, and 9 exhibited the best activity.