247568-48-5

Basic information

• Product Name: 2-(cyclopentylamino)-5-nitrobenzoic acid
• Synonyms: 2-(cyclopentylamino)-5-nitrobenzoic acid
• CAS NO: 247568-48-5
• Molecular Weight: 250.254
• Mol File: 247568-48-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(cyclopentylamino)-5-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(cyclopentylamino)-5-nitrobenzoic acid(247568-48-5)
• EPA Substance Registry System: 2-(cyclopentylamino)-5-nitrobenzoic acid(247568-48-5)

Safety Data

• Hazardous Substances Data: 247568-48-5(Hazardous Substances Data)

Upstream product

• 32203-24-0 5-nitroanthranilic acid ethyl ester 
• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 1003-03-8 Cyclopentamine 
• 1072-72-6 Tetrahydrothiopyran-4-one 
• 247568-49-6 ethyl 5-nitro-2-(tetrahydro-2H-thiopyran-4-ylamino)benzoate 

Downstream Products

• 247568-34-9 2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247569-70-6 N-[4-(tert-butoxycarbonyl)amino-2-chlorobenzyl]-2-(cyclopentylamino)-5-nitrobenzamide 
• 247566-96-7 2-(tert-Butylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247567-01-7 2-(tert-Butoxyamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-86-5 (R)-2-(2-Hydroxy-1-methylethylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-87-6 5-Nitro-N-(1,3-benzodioxol-5-ylmethyl)-2-(2-thiazolylamino)benzamide 
• 247566-83-2 (S)-2-(1-carboxyethylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-85-4 2-(2-Hydroxy-1,1-dimethylethylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247568-38-3 2-[2-Chloro-1-(chloromethyl)ethylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-81-0 (S)-2-[1-(chloromethyl)propylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-91-2 (R)-2-[1-(Methoxycarbonyl)ethylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247567-05-1 (S)-2-[1-(Hydroxymethyl)-2-methylpropylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247568-37-2 2-[2-hydroxy-1-(hydroxymethyl)ethylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247567-91-5 N-(4-amino-2-chlorobenzyl)-2-(cyclopentylamino)-5-nitrobenzamide 

Relevant articles and documents

Novel P2Y12 receptor antagonists

The present invention relates to compounds of Formula I, in which A and B are independently CH2, O, S, NH, C=O, C=NH, C=S or C=N-OH; X is NH, O, S, C=O or CH2 and R1-R5 are as defined in claim 1, which are P2Y12 receptor antagonists and useful for treating, alleviating and/or preventing diseases and disorders related to P2Y12 receptor function as well as pharmaceutical compositions comprising such compounds and methods for preparing such compounds. The present invention is further directed to the use of these compounds, alone or in combination with other therapeutic agents, for the alleviation, prevention and/or treatment of diseases and disorders, especially the use as antithrombotic agents for inhibiting platelet aggregation.

Anthranilic acid derivatives as inhibitors of the cGMP-phosphodiesterase

Compounds of formula (I) STR1where R 1 is hydrogen; R 2 is nitro, cyano or halo(lower)alkyl; R 3 is phenyl substituted with one or more substituents selected from halogen, cyano and lower alkoxy; A is a lower alkylene group; R 4 is a group CR 6 R 7 R 8 wherein R 6 and R 7 form, together with the carbon atom to which they are attached a cycloalkyl group optionally substituted with hydroxy, lower alkoxy or a lower alkanoylamino; and R 8 is hydrogen; its prodrug and a salt thereof.