247568-48-5

Upstream product

• 32203-24-0 5-nitroanthranilic acid ethyl ester 
• 247568-49-6 ethyl 5-nitro-2-(tetrahydro-2H-thiopyran-4-ylamino)benzoate 
• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 1003-03-8 Cyclopentamine 
• 1072-72-6 Tetrahydrothiopyran-4-one 

Downstream Products

• 247568-34-9 2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247567-21-1 2-(Cyclopentylamino)-5-nitro-N-(3-phenylpropyl)benzamide 
• 247567-12-0 2-(Cyclopentylamino)-N-(4-methoxybenzyl)-5-nitrobenzamide 
• 247567-10-8 2-(Cyclopentylamino)-N-(4-fluorobenzyl)-5-nitrobenzamide 
• 247567-18-6 2-(Cyclopentylamino)-N-furfuryl-5-nitrobenzamide 
• 247567-11-9 2-(Cyclopentylamino)-N-(4-methylbenzyl)-5-nitrobenzamide 
• 247567-14-2 2-(Cyclopentylamino)-5-nitro-N-(4-nitrobenzyl)benzamide 
• 247567-19-7 2-(Cyclopentylamino)-5-nitro-N-(thien-2-ylmethyl)benzamide 
• 247567-13-1 2-(Cyclopentylamino)-5-nitro-N-[4-(trifluoromethyl)benzyl]benzamide 
• 247567-15-3 2-(Cyclopentylamino)-N-[4-(dimethylamino)benzyl]-5-nitrobenzamide 
• 247567-17-5 N-(4-Bromobenzyl)-2-(cyclopentylamino)-5-nitrobenzamide 
• 247567-20-0 2-(Cyclopentylamino)-5-nitro-N-phenethylbenzamide 
• 247569-70-6 N-[4-(tert-butoxycarbonyl)amino-2-chlorobenzyl]-2-(cyclopentylamino)-5-nitrobenzamide 
• 247566-96-7 2-(tert-Butylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 

Relevant academic research and scientific papers

Novel P2Y12 receptor antagonists

The present invention relates to compounds of Formula I, in which A and B are independently CH2, O, S, NH, C=O, C=NH, C=S or C=N-OH; X is NH, O, S, C=O or CH2 and R1-R5 are as defined in claim 1, which are P2Y12 receptor antagonists and useful for treating, alleviating and/or preventing diseases and disorders related to P2Y12 receptor function as well as pharmaceutical compositions comprising such compounds and methods for preparing such compounds. The present invention is further directed to the use of these compounds, alone or in combination with other therapeutic agents, for the alleviation, prevention and/or treatment of diseases and disorders, especially the use as antithrombotic agents for inhibiting platelet aggregation.

Catalyst-free microwave-assisted amination of 2-chloro-5-nitrobenzoic acid

(Chemical Equation Presented) The synthesis of N-substituted 5-nitroanthranilic acid derivatives 3a-w was achieved by a new, mild, microwave-assisted, regioselective amination reaction of 5-nitro-2-chlorobenzoic acid (1a) with a diverse range of aliphatic

Anthranilic acid derivatives as inhibitors of the cGMP-phosphodiesterase

Compounds of formula (I) STR1where R 1 is hydrogen; R 2 is nitro, cyano or halo(lower)alkyl; R 3 is phenyl substituted with one or more substituents selected from halogen, cyano and lower alkoxy; A is a lower alkylene group; R 4 is a group CR 6 R 7 R 8 wherein R 6 and R 7 form, together with the carbon atom to which they are attached a cycloalkyl group optionally substituted with hydroxy, lower alkoxy or a lower alkanoylamino; and R 8 is hydrogen; its prodrug and a salt thereof.