247570-04-3

Basic information

• Product Name: BENZO[B]THIOPHEN-2-YLMETHYL-AMMONIUM CHLORIDE
• Synonyms: C-BENZO[B]THIOPHEN-2-YL-METHYLAMINE HYDROCHLORIDE;BENZO[B]THIOPHEN-2-YLMETHYLAMINE HCL;BENZO[B]THIOPHEN-2-YLMETHYL-AMMONIUM CHLORIDE;benzo[b]thiophen-2-ylmethanamine hydrochloride;Benzo[b]thiophene-2-methanamine hydrochloride
• CAS NO: 247570-04-3
• Molecular Formula: C₉H₉NS*ClH
• Molecular Weight: 199.7
• Mol File: 247570-04-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: BENZO[B]THIOPHEN-2-YLMETHYL-AMMONIUM CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZO[B]THIOPHEN-2-YLMETHYL-AMMONIUM CHLORIDE(247570-04-3)
• EPA Substance Registry System: BENZO[B]THIOPHEN-2-YLMETHYL-AMMONIUM CHLORIDE(247570-04-3)

Safety Data

• Hazardous Substances Data: 247570-04-3(Hazardous Substances Data)

Usage

General Description

Benzo[b]thiophen-2-ylmethyl-ammonium chloride is a chemical compound that consists of a benzothiophene group attached to a methyl ammonium chloride group. It is commonly used as a pharmaceutical intermediate in the synthesis of various drugs and organic compounds. BENZO[B]THIOPHEN-2-YLMETHYL-AMMONIUM CHLORIDE has potential applications in the pharmaceutical industry due to its ability to bind to specific receptors and affect biological processes. Additionally, benzo[b]thiophen-2-ylmethyl-ammonium chloride has been studied for its antimicrobial and antifungal properties, making it a potential candidate for use in disinfectants and antiseptics. However, further research is needed to fully understand its potential uses and effects.

Upstream product

• 6314-42-7 benzo[b]thiophene-2-carboxamide 
• 55219-11-9 2-cyanobenzothiophene 

Relevant articles and documents

Silicon hydrogenation reaction method of organic boron and inorganic alkali catalysis amide (by machine translation)

The method is characterized in that organic boron and inorganic bases are used as catalysts, silane is used as a reducing agent, primary amide is reduced to primary amine or dehydration dinitrile, the secondary amide is reduced to a secondary amine or aldimine, and the tertiary amide is reduced to tertiary amine. The method has the advantages of simple operation, mild reaction conditions, wide substrate universality, good functional group compatibility and the like, and has the characteristics of good stability, cheap and accessible catalyst, simple and convenient operation, high practicality and the like. (by machine translation)

A BEt3-Base catalyst for amide reduction with silane

Reported herein is the development of a simple but practical catalytic system for the selective reduction of amides with hydrosilane or hydrosiloxane. Low-cost and readily available triethylborane (1.0 M in THF), in combination with a catalytic amount of an alkali metal base, was found to catalyze the reduction of all three amide classes (tertiary, secondary, and primary amides) to form amines under mild conditions. In addition, the selective transformation of secondary amides to aldimines and primary amides to nitriles can also be achieved by using a proper combination of BEt3 and base. The scope of these BEt3-base-catalyzed amide hydrosilylation reactions has been explored in depth. Preliminary results of mechanistic studies suggest a modified Piers' silane Si-H···B activation mode wherein the hydride abstraction by BEt3 is promoted by the coordination of an alkoxide or hydroxide anion to the Si center.

Anthranilic acid derivatives as inhibitors of the cGMP-phosphodiesterase

Compounds of formula (I) STR1where R 1 is hydrogen; R 2 is nitro, cyano or halo(lower)alkyl; R 3 is phenyl substituted with one or more substituents selected from halogen, cyano and lower alkoxy; A is a lower alkylene group; R 4 is a group CR 6 R 7 R 8 wherein R 6 and R 7 form, together with the carbon atom to which they are attached a cycloalkyl group optionally substituted with hydroxy, lower alkoxy or a lower alkanoylamino; and R 8 is hydrogen; its prodrug and a salt thereof.