24765-53-5

Usage

Uses

Used in Chemical Synthesis:
2-Methyl-2-phenylpropane-1,3-diol serves as a building block in the synthesis of other organic compounds, playing a crucial role in the creation of various chemical products.
Used in Corrosion Inhibition:
As a corrosion inhibitor, 2-methyl-2-phenylpropane-1,3-diol helps protect materials from degradation, making it valuable in industries where metal preservation is essential.
Used in Personal Care and Cosmetics:
Leveraging its hydrating properties, 2-methyl-2-phenylpropane-1,3-diol is incorporated into personal care and cosmetic products to maintain and enhance skin moisture, contributing to healthier and more radiant skin.
Used in Skincare and Hygiene Products:
Due to its antimicrobial properties, 2-methyl-2-phenylpropane-1,3-diol is a beneficial ingredient in skincare and hygiene products, helping to combat harmful microorganisms and promote a cleaner, more hygienic environment.

InChI:InChI=1/C10H14O2/c1-10(7-11,8-12)9-5-3-2-4-6-9/h2-6,11-12H,7-8H2,1H3

Upstream product

• 50-00-0 formaldehyd 
• 34713-70-7 2-Phenylpropanal 
• 21046-14-0 3-methyl-3-phenyloxetan-2-one 
• 81418-06-6 2,2-Di-tert-butyl-5-methyl-5-phenyl-[1,3,2]dioxasilinane 
• 97080-43-8 diethyl 2,2-diphenylmalonate 
• 83-13-6 diethyl 2-phenylmalonate 
• 34009-61-5 diethyl 2-methyl-2-phenylmalonate 

Downstream Products

• 861347-42-4 acetic acid-(3-bromo-2-methyl-2-phenyl-propyl ester) 
• 6248-04-0 2,5-Dimethyl-5-phenyl-[1,3]dioxan 
• 71337-73-0 5-methyl-5-phenyl-[1,3]dioxan-2-one 
• 81418-06-6 2,2-Di-tert-butyl-5-methyl-5-phenyl-[1,3,2]dioxasilinane 
• 161636-10-8 (Z)-1,1,1-trifluoro-4-methoxy-4-phenylbut-3-en-2-one 
• 874470-23-2 3-(3,5-bis(trifluoromethyl)benzyloxy)-2-methyl-2-phenylpropan-1-ol 
• 1354781-06-8 C₃₂H₃₈O₄ 

Relevant academic research and scientific papers

An aryne triggered ring-opening fluorination of cyclic thioethers with potassium fluoride

Herein, we report an aryne triggered ring-opening fluorination protocol of a great variety of saturated sulfur heterocycles. A key factor for the success is the identification of a suitable mediator. Compared to previous methods, this transition-metal free protocol employs low-cost potassium fluoride as the fluorine source. The operational simplicity and mild reaction conditions allow for the rapid synthesis of a wide range of aliphatic fluoride compounds in good yields.

Isomerization of olefins triggered by rhodium-catalyzed C-H bond activation: Control of endocyclic β-hydrogen elimination

Five-membered metallacycles are typically reluctant to undergo endocyclic β-hydrogen elimination. The rhodium-catalyzed isomerization of 4-pentenals into 3-pentenals occurs through this elementary step and cleavage of two C-H bonds, as supported by deuterium-labeling studies. The reaction proceeds without decarbonylation, leads to trans olefins exclusively, and tolerates other olefins normally prone to isomerization. Endocyclic β-hydrogen elimination can also be controlled in an enantiodivergent reaction on a racemic mixture.

Facile reduction of malonate derivatives using NaBH4/Br2: an efficient route to 1,3-diols

Borane-dimethoxyethane generated from sodium borohydride-bromine mixtures efficiently reduces a wide range of malonate derivatives to the corresponding 1,3-diols. This new reagent system represents a milder alternative to current methods available, providing the requisite 1,3-diols in higher yields over shorter reaction times.

ARYLOXYALKYLAMINE NK-1/SSRI INHIBITORS

The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts and solvates, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both.

Unusual Tethering Effects in the Schmidt Reaction of Hydroxyalkyl Azides with Ketones: Cation-π and Steric Stabilization of a Pseudoaxial Phenyl Group

The Lewis acid-promoted reactions of chiral 2-aryl-3-azido-1-propanols with 4-substituted cyclohexanones lead to iminium ethers and ultimately caprolactams (following a hydrolysis step). In this study, it is shown that these reactions afford variable ratios of products, depending on the electronic nature of the phenyl group. These results are interpreted in the context of a cation?π stabilizing effect in the product-determining reaction intermediate. Remarkably, the best selectivity was obtained when an azidopropanol reagent containing a quaternary center was used; a control experiment showed that the high selectivity observed in this result depended upon the free rotation of the pseudoaxial aromatic group in the intermediate that affords the major product. Copyright

THE DI-t-BUTYLSILYLENE PROTECTING GROUP FOR DIOLS

Di-t-butyldichlorosilane reacts with diols to yield the corresponding di-t-butylsilylene derivatives.This useful protecting group is readily removed by treatment with pyridinium hydrofluoride.