24769-56-0 Usage
Uses
Used in Medical Research:
9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID is used as a biomarker for monitoring PGE2 biosynthesis in various medical research applications. Its presence in urine can indicate the level of PGE2 production in the body, which is relevant for understanding certain physiological processes and disease states.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID is used as a reference compound for the development of drugs targeting prostaglandin pathways. Its structural characteristics and metabolic relationship with PGE2 make it a valuable tool for designing and testing new therapeutic agents.
Used in Clinical Diagnostics:
9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID is used as a diagnostic marker in clinical settings to assess the production of PGE2. Measuring the levels of this metabolite in urine samples can help diagnose and monitor conditions related to prostaglandin imbalances, such as inflammation and certain types of cancer.
Used in Toxicology Studies:
In toxicology, 9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID is used as a biomarker to evaluate the effects of toxic substances on prostaglandin metabolism. This can help determine the potential toxicity of certain compounds and their impact on human health.
Check Digit Verification of cas no
The CAS Registry Mumber 24769-56-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,7,6 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 24769-56:
(7*2)+(6*4)+(5*7)+(4*6)+(3*9)+(2*5)+(1*6)=140
140 % 10 = 0
So 24769-56-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H24O7/c17-10(3-1-2-4-15(20)21)5-6-11-12(7-8-16(22)23)14(19)9-13(11)18/h11-13,18H,1-9H2,(H,20,21)(H,22,23)/t11-,12-,13-/m1/s1
24769-56-0Relevant academic research and scientific papers
Preparation of the major urinary metabolite of (-)-prostaglandin E2
Taber, Douglass F.,Gu, Peiming
experimental part, p. 5904 - 5907 (2011/04/15)
The best way to measure whole body production of the locally acting hormone prostaglandin E2 (PGE2) is to assess the accumulation of the major urinary metabolite, PGE2UM. A practical preparation of this delicate
Intermediates in the synthesis of prostaglandins
-
, (2008/06/13)
The invention relates to a new and novel synthesis of prostaglandin E2, and it particularly relates to a novel process starting with relatively inexpensive starting materials. The invention further relates to a synthesis which is readily adaptable for large scale processing because of the high yields in the individual reaction steps. The invention further relates to novel compounds formed as intermediates in the synthesis of prostaglandin E2. The invention still further relates to synthetic analogs and known metabolites of prostaglandin E2 and prostaglandin E1, useful as standards in certain biological assays for determining prostaglandin-like activity.
