24782-72-7

Basic information

• Product Name: 4-Acridinecarboxylic acid, 6-chloro-9,10-dihydro-9-oxo-
• CAS NO: 24782-72-7
• Molecular Formula: C14H8ClNO3
• Molecular Weight: 273.675
• Mol File: 24782-72-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Acridinecarboxylic acid, 6-chloro-9,10-dihydro-9-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Acridinecarboxylic acid, 6-chloro-9,10-dihydro-9-oxo-(24782-72-7)
• EPA Substance Registry System: 4-Acridinecarboxylic acid, 6-chloro-9,10-dihydro-9-oxo-(24782-72-7)

Safety Data

• Hazardous Substances Data: 24782-72-7(Hazardous Substances Data)

Upstream product

• 63329-53-3 lobenzarit 

Downstream Products

• 86611-60-1 6-Chloro-9-(4-methanesulfonylamino-2-methoxy-phenylamino)-acridine-4-carboxylic acid carbamoylmethyl-amide 
• 86611-59-8 6-Chloro-9-(4-methanesulfonylamino-2-methoxy-phenylamino)-acridine-4-carboxylic acid methylamide 
• 86611-57-6 6-Chloro-9-(4-methanesulfonylamino-2-methoxy-phenylamino)-acridine-4-carboxylic acid amide 
• 86611-55-4 6-Chloro-9-(4-methanesulfonylamino-2-methoxy-phenylamino)-acridine-4-carboxylic acid 4-nitro-phenyl ester; hydrochloride 
• 106626-77-1 6-Chloro-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 86632-08-8 p-nitrophenyl 3-chloro-9-oxoacridan-5-carboxylate 

Relevant articles and documents

Potential antitumor agents. 38. 3-Substituted 5-carboxamido derivatives of amsacrine

The synthesis and biological evaluation of a series of 3-substituted 5-carboxamido derivatives of amsacrine (m-AMSA) are described. This series was developed as the result of previous quantitative structure-activity relationship (QSAR) studies of the antitumor activity of 9-anilinoacridine derivatives. In agreement with these studies, this class of compounds, possessing a variety of small nonpolar groups at the 3-position, together with very hydrophilic carboxamido groups at the 5-position, have high in vivo activity against animal leukemia models.