247934-57-2Relevant academic research and scientific papers
Asymmetric Heck reaction of (R) 1-tert-butylsulfinylcyclopentene with arenediazonium salts
Priego, Julián,Carretero, Juan Carlos
, p. 1603 - 1605 (1999)
The asymmetric Heck reaction of the readily available (R) l-tert- butylsulfinyl-l-cyclopentene with a variety of para- and meta- substituted arenediazonium tetrafluoroborates is described. In the presence of Ag2CO3 as base, in CH3CN at rt, the reactions occur in good yields (72-79%) with high diastereoselectivities (de = 82-92%) to afford (3S, SR)-3-aryl-2-tert- butylsulfinyl-1-cyclopentenes as the major adducts. In contrast, poor results were obtained from ortho-substituted arenediazonium salts.
