2480-93-5

Basic information

• Product Name: N-tert-Butoxycarbonyl-N'-benzyloxycarbonyl-L-ornithine
• Synonyms: (S)-5-(((Benzyloxy)carbonyl)aMino)-2-((tert-butoxycarbonyl)aMino)pentanoic acid;N^d-Benzyloxycarbonyl-N^a-Boc-L-ornithine, 98%;Z-Orn(Boc);(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(phenylmethoxycarbonylamino)pentanoic acid;Boc-Orn(Z)-OH >=98.0% (TLC);Nα-Boc-N?-Z-L-ornithine99%;Ndelta-Benzyloxycarbonyl-Nalpha-Boc-L-ornithine;N-DELTA-Z-N-ALPHA-BOC-L-ORNITHINE
• CAS NO: 2480-93-5
• Molecular Formula: C₁₈H₂₆N₂O₆
• Molecular Weight: 366.41
• Product Categories: Amino Acid Derivatives;Amino Acids;Ornithine [Org];Unusual Amino Acids;Amino Acids (N-Protected);Biochemistry;Boc-Amino Acids;Cbz-Amino Acids;Boc-Amino acid series
• Mol File: 2480-93-5.mol
• Article Data: 11

Chemical Properties

• Melting Point: 92.0 to 95.0 °C
• Boiling Point: 579.1 °C at 760 mmHg
• Flash Point: 304 °C
• Appearance: /
• Density: 1.193 g/cm³
• Vapor Pressure: 2.99E-14mmHg at 25°C
• Refractive Index: 1.526
• Storage Temp.: −20°C
• Solubility: almost transparency in Methanol
• PKA: 3.96±0.21(Predicted)
• BRN: 2783761
• CAS DataBase Reference: N-tert-Butoxycarbonyl-N'-benzyloxycarbonyl-L-ornithine(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-Butoxycarbonyl-N'-benzyloxycarbonyl-L-ornithine(2480-93-5)
• EPA Substance Registry System: N-tert-Butoxycarbonyl-N'-benzyloxycarbonyl-L-ornithine(2480-93-5)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 2480-93-5(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C18H26N2O6/c1-18(2,3)26-17(24)20-14(15(21)22)10-7-11-19-16(23)25-12-13-8-5-4-6-9-13/h4-6,8-9,14H,7,10-12H2,1-3H3,(H,19,23)(H,20,24)(H,21,22)/t14-/m0/s1

Upstream product

• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 16937-91-0 N^ε-(benzyloxycarbonyl)ornithine 
• 3304-51-6 N-carboxybenzyl-L-ornithine 
• 501-53-1 benzyl chloroformate 
• 70-26-8 L-ornithine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 16965-08-5 1,1-dimethylethyl 2,4,5-trichlorophenyl carbonate 

Downstream Products

• 143139-11-1 Boc-Orn(Z)-CH₂Cl 
• 88489-27-4 Nα-tert-butoxyacrbonyl-Nδ-benzyloxycarbonyl-L-ornityl-L-leucine methyl ester 
• 75243-99-1 (S)-5-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-pentanoic acid 3-oxo-2-phenyl-3H-inden-1-yl ester 
• 97868-80-9 N-benzyloxycarbonyl-2-aminoethyl ester of N^α-tert-butyloxycarbonyl-N^δ-benzyloxycarbonyl-L-ornithine 
• 138865-33-5 [(S)-4-(4-Benzoyl-phenylcarbamoyl)-4-tert-butoxycarbonylamino-butyl]-carbamic acid benzyl ester 
• 99215-72-2 Boc-Orn(Z)-Phe-Pro-OEt 
• 99215-71-1 Boc-Orn(Z)-Phe-D-Pro-OEt 
• 19792-07-5 N_α-tBoc-N_δ-Cbz-L-ornithine 4-nitrophenyl ester 
• 62430-16-4 Boc-Orn(Z)-Leu-OEt 
• 159877-12-0 (R)-5-amino-2-((tert-butoxycarbonyl)amino)pentanoic acid 
• 209269-81-8 ((S)-5-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-pentanoylamino)-acetic acid (benzhydryl-carbamoyl)-methyl ester 
• 139178-70-4 ((S)-4-tert-Butoxycarbonylamino-4-methylcarbamoyl-butyl)-carbamic acid benzyl ester 
• 220183-15-3 [(S)-4-tert-Butoxycarbonylamino-4-((S)-3-methyl-1-methylcarbamoyl-butylcarbamoyl)-butyl]-carbamic acid benzyl ester 
• 174699-01-5 (2R,4R)-1-((S)-5-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-pentanoyl)-4-methyl-piperidine-2-carboxylic acid ethyl ester 

Relevant articles and documents

COMPOUND FOR IMPROVING L-ARGININE BIOAVAILABILITY

The present application relates to a compound which may be useful for mediating NO production and improving L-arginine bioavailability in a subject. Pharmaceutical compositions comprising the compound and methods of using the compound are also provided.

CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS

The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.

Synthetic studies on chlorofusin: Synthesis of the cyclic peptide portion

The cyclic peptide portion of chlorofusin was synthesized by condensation of the five segments, d-Ada-OTMSE, Boc-l.-Orn(Cbz), Boc-l-Thr-l-Ala, l-Asn(Tr)-d-Asn(Tr)-d-Leu-OTMSE, and Boc-l-Thr-d-Leu, followed by cyclization at the amide bond between d-Ada an