2482-80-6 Usage
Uses
Used in Oncology:
2,6-Bis(1-aziridinyl)-4-chloropyrimidine is used as an antineoplastic agent for the treatment of various types of cancers, such as leukemia, lymphoma, and solid tumors. It is effective in inhibiting the replication and transcription processes in cancer cells by forming covalent bonds with DNA, resulting in the formation of interstrand and intrastrand crosslinks.
Used in Cancer Research:
In the field of cancer research, 2,6-Bis(1-aziridinyl)-4-chloropyrimidine serves as a valuable tool for studying the mechanisms of DNA crosslinking and its effects on cancer cell replication and transcription. This knowledge can contribute to the development of novel therapeutic strategies and the identification of potential targets for cancer treatment.
Used in Drug Development:
2,6-Bis(1-aziridinyl)-4-chloropyrimidine is utilized in the development of new antineoplastic drugs, as its DNA crosslinking properties can be harnessed to create more effective and targeted cancer therapies. Researchers are working to modify the compound to reduce its toxicity and genotoxicity while maintaining or enhancing its antineoplastic activity.
Used in Drug Delivery Systems:
To overcome the limitations of 2,6-Bis(1-aziridinyl)-4-chloropyrimidine, such as its high toxicity and potential genotoxicity, novel drug delivery systems are being developed. These systems aim to improve the compound's delivery, bioavailability, and therapeutic outcomes by encapsulating it within organic or metallic nanoparticles, liposomes, or other carriers, allowing for more precise targeting of cancer cells and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 2482-80-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,8 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2482-80:
(6*2)+(5*4)+(4*8)+(3*2)+(2*8)+(1*0)=86
86 % 10 = 6
So 2482-80-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H9ClN4/c9-6-5-7(12-1-2-12)11-8(10-6)13-3-4-13/h5H,1-4H2
