248256-29-3Relevant academic research and scientific papers
Studies on the generation of enolate anions from butane-2,3-diacetal protected glycolic acid derivatives and subsequent highly diastereoselective coupling reactions with aldehydes and acid chlorides
Ley, Steven V.,Dixon, Darren J.,Guy, Richard T.,Palomero, Maria A.,Polare, Alessandra,Rodriguez, Felix,Sheppard, Tom D.
, p. 3618 - 3627 (2007/10/03)
Highly diastereoselective coupling reactions of enolates derived from butane-2,3-diacetal protected glycolic acids 1 and 2 and their alkylated derivatives with aldehydes are reported together with their efficient acid-catalysed deprotection to yield enant
Highly diastereoselective lithium enolate aldol reactions of butane-2,3-diacetal desymmetrized glycolic acid and deprotection to enantiopure anti-2,3-dihydroxy esters.
Dixon,Ley,Polara,Sheppard
, p. 3749 - 3752 (2007/10/03)
[reaction--see text] The butane-2,3-diacetal (BDA) desymmetrized glycolic acid building block 1 undergoes efficient and highly diastereoselective lithium enolate aldol reactions with both aromatic and aliphatic aldehydes to afford, after an acidic methano
Stoffwechselproducte von Mikroorganismen. Strukturaufklaerung von Elaiophylin: Spektroskopische Untersuchungen und Abbau
Kaiser, Hanspeter,Keller-Schierlein, Walter
, p. 407 - 424 (2007/10/02)
The structure of the antibiotic elaiophylin (azalomycin B) was elucidated by extended spectroscopic investigations and chemical degradation.Elaiophylin (26) is a macrodiolide with a 16 membered dilactone ring.The synthesis of 7-acetoxy-6-ethyl-3-octanone (14), the acetyl derivative of an important degradation product, is described.
