24829-12-7Relevant articles and documents
Structure investigations of Schiff bases derived from 3-amino-1H-1,2,4-triazole
Ko?odziej, Beata,Morawiak, Maja,Schilf, Wojciech,Kamieński, Bohdan
, p. 207 - 218 (2019)
In the present paper, twelve Schiff bases derived from 3-amino-1H-1,2,4-triazole (ATz) and various benzaldehydes, and salicylaldehydes were synthesized. The 1H, 13C, and 15N NMR data are discussed in relation to the structure of ATz and its imine products. In addition, X-ray, ATR-FTIR, and UV–Vis analytical techniques are used for structure elucidation of ATz-based Schiff bases. It was found that the starting material, 3-amino-1H-1,2,4-triazole, exists as tautomeric mixture of three forms (Graphical Abstract) in solution, whereas in the solid state (13C and 15N CPMAS data) potentially tautomeric proton is located on nitrogen atom traditionally marked as N-2 (Graphical Abstract, 2N–H structure). All investigated Schiff bases derived from salicylaldehydes exist in both phases as tautomeric equilibrium mixtures, where enol-imine forms are dominated structures. The positions of those equilibria only very slightly depend on substituents in phenol ring. Generally, the contributions of keto-amine forms in the solid state are higher comparing with DMSO solutions.
Scrutinizing the DNA damaging and antimicrobial abilities of triazole appended metal complexes
Utthra, Ponnukalai Ponya,Pravin, Narayanaperumal,Raman, Natarajan
, p. 136 - 144 (2016)
New mononuclear transition metal complexes 1-12 bearing the bioactive triazole analogues were synthesized and characterized by elemental analysis and spectroscopic techniques. The interaction of calf thymus DNA (CT-DNA) with the synthesized compounds was
Antiglycation activity of triazole schiff’s bases against fructose-mediated glycation: In vitro and in silico study
Choudhary, Muhammad I.,Imad, Rehan,Khan, Khalid M.,Naqeeb, Uzma,Shaikh, Muniza,Siddiqui, Salman,Subzwari, Fakiha,Zafar, Humaira
, p. 575 - 591 (2020/06/21)
Background: Advanced glycation end products (AGEs) are known to be involved in the pathophysiology of diabetic complications, neurodegenerative diseases, and aging. Preventing the formation of AGEs can be helpful in the management of these diseases. Objec