248582-40-3

Upstream product

• 248582-39-0 (1S,2R,3R,4S,5R)-2,4-dibenzyloxy-5-benzyloxycarbonylamino-3-<(t-butyldimethylsilyl)oxy>cyclohept-6-en-1-ol 
• 185383-34-0 (5R,6S,7S)-5,7-dibenzyloxy-6-[(t-butyldimethylsilyl)oxy]cyclohepta-1,3-diene 
• 248582-38-9 (1R,2S,3S,4R,5S)-2,4-dibenzyloxy-8-benzyloxycarbonyl-3-<(t-butyldimethylsilyl)oxy>-9-oxa-8-azabicyclo-<3.2.2>-non-6-ene 
• 248582-36-7 (1S,2R,3R,4S,5R)-2,4-dibenzyloxy-3-<(t-butyldimethylsilyl)oxy>-9-oxa-8-azabicyclo-<3.2.2>-non-6-ene 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 248582-41-4 (2S,3R,4S,5R)-2,4-dibenzyloxy-5-benzyloxycarbonylamino-3-hydroxycyclohept-6-en-1-one 
• 127414-85-1 calystegin B2 

Relevant academic research and scientific papers

General access to polyhydroxylated nortropane derivatives through hetero Diels-Alder cycloadditions. Part 3: Synthesis of natural (+)-calystegine B2

Cycloaddition of chiral nitroso derivatives with cyclohepta-1,3-diene gave one single stereoisomer with an excellent selectivity. The structures including absolute configurations have been assigned by spectroscopy and X-ray crystallography. These studies have been applied to the total synthesis of the naturally occurring calystegine B2.