2486-66-0

Basic information

• Product Name: 2-ETHOXY-4-NITROBENZOIC ACID
• Synonyms: 4-NITRO-2-ETHOXYBENZOIC ACID;2-ETHOXY-4-NITROBENZOIC ACID;2-Carboxy-5-nitrophenetole, 4-Carboxy-3-ethoxynitrobenzene
• CAS NO: 2486-66-0
• Molecular Formula: C₉H₉NO₅
• Molecular Weight: 211.17
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;C9;Carbonyl Compounds;Carboxylic Acids;Building Blocks;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks
• Mol File: 2486-66-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 148-151 °C(lit.)
• Boiling Point: 395.9°C at 760 mmHg
• Flash Point: 193.3°C
• Appearance: /
• Density: 1.368g/cm³
• Vapor Pressure: 5.58E-07mmHg at 25°C
• Refractive Index: 1.575
• PKA: 3.24±0.13(Predicted)
• CAS DataBase Reference: 2-ETHOXY-4-NITROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHOXY-4-NITROBENZOIC ACID(2486-66-0)
• EPA Substance Registry System: 2-ETHOXY-4-NITROBENZOIC ACID(2486-66-0)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 2486-66-0(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C9H9NO5/c1-2-15-8-5-6(10(13)14)3-4-7(8)9(11)12/h3-5H,2H2,1H3,(H,11,12)

Upstream product

• 2486-63-7 2-ethoxy-1-methyl-4-nitrobenzene 
• 910572-96-2 2-ethoxy-4-nitro-benzoic acid ethyl ester 
• 619-19-2 2-hydroxy-4-nitrobenzoic acid 

Downstream Products

• 24091-87-0 methyl 2-ethoxy-4-nitrobenzoate 
• 910572-96-2 2-ethoxy-4-nitro-benzoic acid ethyl ester 
• 39614-84-1 2-ethoxy-4-nitro-benzoyl chloride 
• 59-07-4 2-ethoxy-4-aminobenzoic acid 
• 408328-89-2 2-ethoxy-4,5-dinitro-benzoic acid 
• 121759-16-8 2-ethoxy-4-nitro-benzoic acid-(3-diethylamino-propylamide) 
• 636582-66-6 4-(tert-butoxy-carbonyl-amino)-2-ethoxy-benzoic acid 
• 2486-55-7 methyl 2-ethoxy-4-acetamidobenzoate 

Relevant articles and documents

2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The present invention relates to novel oxadiazole derivatives of formula (1) having pharmacological activity, processes for their preparation, compositions containing them and their use in the treatment of neurological, psychiatric disorders and gastrointestinal disorders through modulation of the nicotinic α7 receptor formula (I).