248603-82-9Relevant academic research and scientific papers
3-HYDROXY-IMIDAZOLIDIN-4-ONE COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE
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Page/Page column 38, (2019/03/17)
The invention relates to a compound of Formula (I) : Formula (I), or pharmaceutically acceptable enantiomers, or salts thereof. The present invention also relates to the use of compounds of Formula (I) as selective inhibitors of indoleamine 2,3-dioxygenas
INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE
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Page/Page column 38, (2017/09/28)
The invention relates to a compound of Formula (I), or pharmaceutically acceptable enantiomers, or salts thereof. The present invention also relates to the use of compounds of Formula (I) as selective inhibitors of indoleamine 2,3-dioxygenase. The inventi
TETRAHYDROISOQUINOLINE DERIVATIVES
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Page/Page column 92-93, (2016/05/02)
The present invention relates to tetrahydroisoquinoline derivatives according to formula (I), which are Positive Allosteric Modulators of D1 and accordingly of benefit as pharmaceutical agents for the treatment of diseases in which D1 receptors play a role.
A short way to switchable carbenes
Hashmi, A. Stephen K.,Lothschuetz, Christian,Graf, Katharina,Haeffner, Tobias,Schuster, Andreas,Rominger, Frank
supporting information; experimental part, p. 1407 - 1412 (2011/08/07)
A new, one-step route to N-heterocyclic oxo-carbene complexes (NHOCs), representatives of chemo-switchable NHC complexes, is reported. This simple procedure provides an easy access to gold, palladium and platinum complexes of these ligands. Copyright
1,3-dipolar cycloaddition of nitrones with 5-methylenehydantoins: Synthesis and transformation of new spirohydantoin derivatives
Bahy, Amira,Kacem, Yakdhane,Hassine, Bechir Ben
experimental part, p. 1377 - 1390 (2010/06/21)
1,3-Dipolar cycloaddition of various acyclic nitrones with 5-methylenehydantoin derivatives afforded new chiral spiroadducts in good yields. All the spirohydantoins were obtained through a regio-and stereospecific pathway, and the spirocarbon atom was linked to the isoxazolidine oxygen atom. A representative example of the reduction of the spirohydantoin 8 with Zn/AcOH led to the substituted 1,3-aminoalcohol hydantoin 20.
Functionalized alkyl and alenyl side chain derivatives of glycinamides as farnesyl transferase inhibitors
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, (2008/06/13)
The present invention provides compounds of Formula (I). The present invention also provides a method of treating cancer and treating or preventing restenosis or atherosclerosis. Also provided by the present invention is a pharmaceutically acceptable comp
