24885-31-2Relevant academic research and scientific papers
An oxidative amidation and heterocyclization approach for the synthesis of β-carbolines and dihydroeudistomin y
Meruva, Suresh Babu,Raghunadh, Akula,Kamaraju, Raghavendra Rao,Kumar, U.K. Syam,Dubey
, p. 471 - 480 (2014/03/21)
A novel synthetic methodology has been developed for the synthesis of dihydro-β-carboline derivatives employing oxidative amidation-Bischler- Napieralski reaction conditions using tryptamine and 2,2-dibromo-1- phenylethanone as key starting materials. A number of dihydro-β-carboline derivatives have been synthesized in moderate to good yields using this methodology. Attempts were made towards the conversion of these dihydro-β-carbolines to naturally occurring eudistomin alkaloids.
