248922-89-6

Upstream product

• 61-90-5 L-leucine 
• 108-94-1 cyclohexanone 

Downstream Products

• 248921-74-6 (S)-2-Cyclohexylamino-4-methyl-pentanoic acid [4,4-bis-(4-fluoro-phenyl)-butyl]-amide monohydrochloride 
• 248922-00-1 (S)-1-{4-[Bis-(4-fluoro-phenyl)methyl]-piperazin-1-yl}-2-cyclohexylamino-4-methyl-pentan-1-one 
• 217172-29-7 (S)-2-(Cyclohexyl-methyl-amino)-4-methyl-pentanoic acid 

Relevant academic research and scientific papers

A simple method for preparation of N-mono- and N,N-di-alkylated α-amino acids

Reactions of α-amino acids with ketones under hydrogenation conditions using 20% Pd(OH)2/C as the catalyst gave N-mono-alkylated amino acids in high yields. Reductive methylation of N-mono-alkylated amino acids under the same hydrogenation cond