24919-37-7

Basic information

• Product Name: 3-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
• Synonyms: 3-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione;3-Methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-2,5-dione
• CAS NO: 24919-37-7
• Molecular Formula: C10H10N2O2
• Molecular Weight: 190.2
• Mol File: 24919-37-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 320.5-321 °C
• Boiling Point: 510.2°Cat760mmHg
• Flash Point: 238.5°C
• Appearance: /
• Density: 1.195g/cm³
• Vapor Pressure: 1.58E-10mmHg at 25°C
• Refractive Index: 1.542
• PKA: 12.98±0.40(Predicted)
• CAS DataBase Reference: 3-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione(24919-37-7)
• EPA Substance Registry System: 3-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione(24919-37-7)

Safety Data

• Hazardous Substances Data: 24919-37-7(Hazardous Substances Data)

Usage

General Description

3-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione is a chemical compound with the molecular formula C9H10N2O2. It is a heterocyclic compound containing a benzodiazepine ring system and a lactam functional group. 3-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione is a derivative of the benzodiazepine class of psychoactive drugs, which are commonly used as sedatives, hypnotics, and anxiolytics. The 3-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione is known to exhibit central nervous system depressant effects and has potential medicinal applications in the treatment of anxiety, insomnia, and other neurological disorders. However, it is important to note that this compound may also have addictive and potentially harmful effects if used improperly.

InChI:InChI=1/C10H10N2O2/c1-6-9(13)12-8-5-3-2-4-7(8)10(14)11-6/h2-6H,1H3,(H,11,14)(H,12,13)

Upstream product

• 68790-38-5 2-(tert-butyloxycarbonylamino)benzoic acid 
• 90-16-4 1,2,3-benzotriazin-4(3H)-one 
• 56-41-7 L-alanin 
• 118-48-9 isatoic anhydride 
• 302-72-7 rac-Ala-OH 

Relevant articles and documents

Simple synthesis, structure and ab initio study of 1,4-benzodiazepine-2,5- diones

A simple procedure for the synthesis of pyrido[2,1-c][1,4] benzodiazepine-6,12-dione (1) and 1,4-benzodiazepine-2,5-diones (2a-2d), using microwave irradiation and/or conventional heating is reported. The configuration of 1 was determined by single-crysta

Solid phase synthesis of 1,4-benzodiazepine-2,5-diones

1,4-benzodiazepine-2,5-diones were synthesized by a simple procedure utilizing polymer supported amino acids and o-nitrobenzoic acids or protected anthranilic acids. Cyclization of the common aminoamide intermediate with concomitant release from the support furnished the desired 1,4-benzodiazepine-2,5-diones. The products were recovered in high yields and exhibited excellent purities.

New synthesis of 1,4 benzodiazepine-2,5-diones by means of HCl gas catalyst

A new synthesis of 1,4-benzodiazepinediones 4, particularly 1,4-dihydro1H-1,4-benzodiazepine-2,5-dione, 4c key intermediate of metabolites cyclopenin 9, cyclopenol 10, cyclopeptine 11 and dehydrocyclopeptide 12, was achieved by action of dry HCl gas in DM