249516-41-4

Basic information

• Product Name: 3-{4-nitrophenyl}acrylaldehyde N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiosemicarbazone
• Synonyms: 3-{4-nitrophenyl}acrylaldehyde N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiosemicarbazone
• CAS NO: 249516-41-4
• Molecular Formula: C21H20N6O3S
• Molecular Weight: 436.49
• Mol File: 249516-41-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 569.2±60.0 °C(Predicted)
• Appearance: /
• Density: 1.32±0.1 g/cm3(Predicted)
• PKA: 10.48±0.20(Predicted)
• CAS DataBase Reference: 3-{4-nitrophenyl}acrylaldehyde N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiosemicarbazone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{4-nitrophenyl}acrylaldehyde N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiosemicarbazone(249516-41-4)
• EPA Substance Registry System: 3-{4-nitrophenyl}acrylaldehyde N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiosemicarbazone(249516-41-4)

Safety Data

• Hazardous Substances Data: 249516-41-4(Hazardous Substances Data)

Upstream product

• 83-07-8 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one 
• 1734-79-8 3-(4-nitrophenyl)-2-propenal 
• 96447-49-3 4-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)thiosemicarbazide 

Relevant articles and documents

New thiazolidones-4 with pyrazolone-5 substituent as the potential NSAIDs

The synthesis of a group of thiazolidine derivatives with pyrazolone-5 substituent is described. The structure of the new compounds is supported by 1H- and 13C-NMR spectra. Group of compounds was tested in vivo for their antiinflammatory activity. The obtained results gave the opportunity to separate the perspective groups of potential NSAIDs, which have got greater antiinflammatory activity than the best standard drugs.