24955-08-6Relevant academic research and scientific papers
Discovery of styrylaniline derivatives as novel alpha-synuclein aggregates ligands
Bian, Jiang,Liu, Yi-Qi,He, Jie,Lin, Xin,Qiu, Chen-Yang,Yu, Wen-Bo,Shen, Yan,Zhu, Ze-Yun,Ye, De-Yong,Wang, Jian,Chu, Yong
, (2021/10/06)
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Early diagnosis is the key to treatment but is still a great challenge in the clinic now. The discovery of alpha-synuclein (α-syn) aggregates ligands has become an attractive s
Non-competitive and selective dipeptidyl peptidase IV inhibitors with phenethylphenylphthalimide skeleton derived from thalidomide-related α-glucosidase inhibitors and liver X receptor antagonists
Motoshima, Kazunori,Sugita, Kazuyuki,Hashimoto, Yuichi,Ishikawa, Minoru
, p. 3041 - 3045 (2011/06/24)
Novel dipeptidyl peptidase IV (DPP-IV) inhibitors with a phenethylphenylphthalimide skeleton were prepared based on α-glucosidase inhibitors and liver X receptor (LXR) antagonists derived from thalidomide. Representative compounds showed non-competitive i
