249552-14-5

Upstream product

• 148903-03-1 (-)-(1S,4R,4aS,5S,8aS)-5-acetoxy-1,4,4a,8a-tetrahydro-endo-1,4-methanonaphthalen-8(5H)-one 
• 146830-36-6 (+)-(1S,4R,4aS,5R,8S,8aR)-5-Acetoxy-1,4,4a,5,8,8a-hexahydro-8-hydroxy-endo-1,4-methanonaphthalene 
• 249552-10-1 (1R,4S,4aR,5S,7R,8S,8aS)-8-(tert-Butyl-dimethyl-silanyloxy)-7-(6-methoxy-pyridin-3-yl)-1,4,4a,5,6,7,8,8a-octahydro-1,4-methano-naphthalen-5-ol 
• 249552-08-7 (1R,4S,4aR,7R,8S,8aS)-8-(tert-Butyl-dimethyl-silanyloxy)-7-(6-methoxy-pyridin-3-yl)-4,4a,6,7,8,8a-hexahydro-1H-1,4-methano-naphthalen-5-one 
• 249552-06-5 (1R,4S,4aR,8R,8aS)-8-hydroxy-4,4a,8,8a-tetrahydro-[1,4]methanonaphthalen-5(1H)-one 
• 162809-79-2 (1R,4S,4aR,8R,8aS)-8-{[(1,1-dimethylethyl)dimethylsilyl]oxy}-4,4a,8,8a-tetrahydro[1,4]methanonaphthalen-5(1H)-one 
• 249552-12-3 (1S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(6-methoxy-pyridin-3-yl)-cyclohex-2-enol 

Downstream Products

• 249552-17-8 5-[(1R,2S,5S)-5-Azido-2-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl]-2-methoxy-pyridine 
• 249552-22-5 Methanesulfonic acid (1S,2R,4S)-4-azido-2-(6-methoxy-pyridin-3-yl)-cyclohexyl ester 
• 249552-19-0 (1S,2R,4S)-4-Azido-2-(6-methoxy-pyridin-3-yl)-cyclohexanol 
• 140111-52-0 epibatidine 
• 249552-15-6 Methanesulfonic acid (1R,3R,4S)-4-(tert-butyl-dimethyl-silanyloxy)-3-(6-methoxy-pyridin-3-yl)-cyclohexyl ester 

Relevant academic research and scientific papers

A stereocontrolled route to (-)-epibatidine using a chiral cis-cy clohexadiene-1, 4-diol equivalent

A concise diastereo- and enantio-controlled synthesis of (-)-epibatidine, the potent analgesic alkaloid from an Ecuadoran poison frog, Epipedobates tricolor, has been developed starting with a synthetic equivalent of chiral cw-cyclohexadiene-1, 4-diol. Th