2496-90-4

Usage

Uses

Used in Cosmetics and Personal Care Products:
4-Hydroxybenzoic acid 2-hydroxyethyl ester is used as a preservative in cosmetics and personal care products to prevent microbial growth and extend the shelf life of these products. Its antimicrobial properties help maintain the quality and safety of these products for consumers.
Used in Pharmaceuticals:
In the pharmaceutical industry, 4-Hydroxybenzoic acid 2-hydroxyethyl ester is used as an excipient or an inactive ingredient. It aids in the delivery of the active ingredients of a medication, enhancing the efficacy and stability of the final product.
Ongoing Research:
While considered safe for use in low concentrations, there is ongoing research into the potential effects of 4-Hydroxybenzoic acid 2-hydroxyethyl ester on human health. This research aims to further understand its safety profile and ensure its continued use in various applications without posing any health risks to consumers.

InChI:InChI=1/C9H10O4/c10-5-6-13-9(12)7-1-3-8(11)4-2-7/h1-4,10-11H,5-6H2

Upstream product

• 120-47-8 Ethyl 4-hydroxybenzoate 
• 57045-26-8 4-Ethoxycarbonyloxybenzoyl chloride 
• 15552-32-6 4-Ethoxycarbonyloxybenzoic acid 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 1609114-83-1 2-hydroxyethyl 4-(1,1,2-trifluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)ethoxy)benzoate 

Relevant academic research and scientific papers

Solar photocatalytic decomposition of ethyl paraben in zinc oxide suspensions

The photocatalytic degradation of ethyl paraben (EP) in zinc oxide (ZnO) suspensions under simulated solar radiation was investigated. The effect of EP concentration (500–1500 μg/L), ZnO concentration (100–500 mg/L), reaction time (3–9 min), initial pH (3–9), light intensity (7.3 10?7–1.1 10?6 einstein/(L.s)) and the water matrix (0–10 mg/L of humic acid) on degradation was evaluated implementing a factorial design methodology. Of the six variables tested, EP concentration, ZnO concentration, reaction time and the water matrix were found to be statistically significant variables, and also important was the second order interaction of EP concentration with reaction time. With the exception of the water matrix, all other effects were positive with respect to the concentration of EP removed. Experiments at increased EP concentration (20 mg/L) were performed to identify transformation products (TPs) and assess the extent of mineralization. LC-TOF-MS analysis revealed the formation of seven early-stage TPs through hydroxylation and dealkylation reactions and a plausible reaction pathway was proposed. Besides the identified TPs, other unidentified TPs were also formed as has been verified measuring the extent of mineralization and performing a carbon balance in the liquid phase. EP at 20 mg/L exhibited mild estrogenic activity, which was partially removed upon oxidation. The stability of ZnO was evaluated measuring the extent of zinc leaching, which was just 1.5%; moreover, ZnO was found to be more active than reference P25 TiO2 for EP degradation and mineralization.