249622-68-2

Basic information

• Product Name: 2,4-dimethoxymethoxy3,5-di-C-prenylacetophenone
• CAS NO: 249622-68-2
• Molecular Weight: 376.493
• Mol File: 249622-68-2.mol

Chemical Properties

• CAS DataBase Reference: 2,4-dimethoxymethoxy3,5-di-C-prenylacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dimethoxymethoxy3,5-di-C-prenylacetophenone(249622-68-2)
• EPA Substance Registry System: 2,4-dimethoxymethoxy3,5-di-C-prenylacetophenone(249622-68-2)

Safety Data

• Hazardous Substances Data: 249622-68-2(Hazardous Substances Data)

Upstream product

• 6515-05-5 2',4'-bis(methoxymethoxy)acetophenone 
• 870-63-3 prenyl bromide 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 

Downstream Products

• 52601-08-8 2',4'-dihydroxy-3',5'-di-C-prenylchalcone 
• 59920-27-3 7-hydroxy-6,8-di-C-prenylflavanone 

Relevant articles and documents

Synthesis of 7-hydroxy-6,8-di-C-prenyl-flavanone

The synthesis of flavanone A 8, a constituent of the leaves and bark of Milletia ovalifolia is described. β-Resacetophenone 1 on treatment with methoxymethyl chloride afford 2,4-dimethoxymethoxyacetophenone 2 which on nuclear prenylation yield 2,4-dimethoxymethoxy-3,5-di-C-prenylacetophenone 5. Alkaline condensation of 5 with benzaldehyde give 2',4'-dimethoxymethoxy- 3',5'-di-C-prenylchalcone 6. 2',4'-Dihydroxy-3',5'-di-C-prenylchalcone 7 obtained by the demethoxymethylation of 6, on treatment with NaOAc/EtOH furnish 7-hydroxy-6,8-di-C- prenylflavanone (8, flavanone A).